SynthesisQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2012
Health-related quality of life among children with mental disorders: a systematic review.
Synthesis in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Contextual determinants associated with children's and adolescents' mental health care utilization: a systematic review.European child & adolescent psychiatry · 2024Pooled it
- The Impact of Childhood Attention-Deficit/Hyperactivity Disorder (ADHD) on Children's Health-Related Quality of Life: A Systematic Review and Meta-Analysis.Journal of attention disorders · 2023Pooled it
- Quality of life, psychological adjustment, and adaptive functioning of patients with intoxication-type inborn errors of metabolism - a systematic review.Orphanet journal of rare diseases · 2014Pooled it
- Usefulness of Interventions Using a Smartphone Cognitive Behavior Therapy Application for Children With Mental Health Disorders: Prospective, Single-Arm, Uncontrolled Clinical Trial.JMIR formative research · 2025Trial
- The Building Regulation in Dual-Generations Program (BRIDGE): A Mixed-Methods Feasibility Pilot of a Parenting Program for Depressed Mothers of Preschoolers, Matched with Dialectical Behavior Therapy Skills.Child psychiatry and human development · 2023Trial
- Association between comorbid anxiety and depression symptomatology, quality of life, social support and use of mental health services in youth from Bogota, Buenos Aires, and Lima.Journal of affective disorders · 2026Article
- "What impact does having a diagnosis of an inherited cardiac condition have on children and young people's physical activity and quality of life?" A scoping review.European journal of pediatrics · 2026Article
- The Long-Term Impact of ADHD on Children and Adolescents' Health-Related Quality of Life: Results From a Longitudinal Population-Based Australian Study.Journal of attention disorders · 2025Article
- Article
- Health-Related Quality of Life Among Unaccompanied Refugee Minors Settled in a Norwegian Municipality.Journal of child & adolescent trauma · 2025Article
- Child Wellbeing during the COVID-19 Pandemic: A Multi-cohort Comparison and a Multi-informant Genetic Study.Behavior genetics · 2025Article
- Pathways between Child Maltreatment, Psychological Symptoms, and Life Satisfaction: A Network Analysis in Adolescent Inpatients.Research on child and adolescent psychopathology · 2024Article
- Snapshot of knowledge and stigma toward mental health disorders and treatment in Spain.Frontiers in psychology · 2024Article
- Measuring mental health action competencies in school teachers: internal and external validity evidence.Frontiers in digital health · 2024Article
- Article
- Treatment outcome of an intensive psychiatric home treatment for children and adolescents: a non-randomized controlled pilot evaluation.European child & adolescent psychiatry · 2023Article
- Persons With Spinal Cord Injury Report Peripherally Dominant Serotonin-Like Syndrome After Use of Serotonergic Psychedelics.Neurotrauma reports · 2023Article
- Self-help Digital Interventions Targeted at Improving Psychological Well-being in Young People With Perceived or Clinically Diagnosed Reduced Well-being: Systematic Review.JMIR mental health · 2022Review
- The relationship between physical and mental health multimorbidity and children's health-related quality of life.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022Article
- Risk and protective factors of quality of life for children with autism spectrum disorder and their families during the COVID-19 lockdown. An Italian study.Research in developmental disabilities · 2022Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo systematically review studies about the quality of life (QOL) of children with various mental disorders relative to healthy controls and to describe limitations in these studies.
methodsRelevant articles were searched using different databases, by checking reference lists and contacting experts. We included articles that either compared children with mental disorders to healthy controls/norm values or made such a comparison possible.
resultsSixteen out of 4,560 articles met the pre-defined inclusion criteria. These studies revealed that the QOL of children with various mental disorders is compromised across multiple domains. The largest effect sizes were found for psychosocial and family-related domains and for the total QOL score, whereas physical domains generally were less affected. The most important limitations in the existing literature include the lack of study samples drawn from the general population, the failure to use self-ratings, not considering item overlap between measuring QOL and assessing for the presence of a particular mental disorder, and not determining whether the children were receiving medication for their mental disorder.
conclusionsChildren with mental disorders experience a considerable reduction in QOL across various domains. Research studies that avoid previous limitations are crucial to fill existing knowledge gaps.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.