Is FTO a type 2 diabetes susceptibility gene?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

12 citing papers in PubMed.

1. Associations of the FTO rs9939609 and the MC4R rs17782313 polymorphisms with type 2 diabetes are modulated by diet, being higher when adherence to the Mediterranean diet pattern is low.Cardiovascular diabetology · 2012
   Trial
2. Association of FTO gene variant rs9939609 with polycystic ovary syndrome from Gujarat, India.BMC medical genomics · 2023
   Article
3. Effect of FTO rs9939609 variant on insulin resistance in obese female adolescents.BMC research notes · 2018
   Article
4. The (FTO) gene polymorphism is associated with metabolic syndrome risk in Egyptian females: a case- control study.BMC medical genetics · 2017
   Article
5. Longitudinal relationships between glycemic status and body mass index in a multiethnic study: evidence from observational and genetic epidemiology.Scientific reports · 2016
   Article
6. Association of FTO rs9939609 SNP with Obesity and Obesity- Associated Phenotypes in a North Indian Population.Oman medical journal · 2016
   Article
7. FTO Gene Polymorphism Is Associated with Type 2 Diabetes through Its Effect on Increasing the Maximum BMI in Japanese Men.PloS one · 2016
   Article
8. Fat mass and obesity-associated gene rs11642015 polymorphism is significantly associated with prediabetes and type 2 diabetes subsequent to adjustment for body mass index.Biomedical reports · 2014
   Article
9. Genetic susceptibility to type 2 diabetes and obesity: from genome-wide association studies to rare variants and beyond.Diabetologia · 2014
   Review
10. BMI-associated alleles do not constitute risk alleles for polycystic ovary syndrome independently of BMI: a case-control study.PloS one · 2014
    Article
11. The role of adiposity in cardiometabolic traits: a Mendelian randomization analysis.PLoS medicine · 2013
    Article
12. Replication of type 2 diabetes candidate genes variations in three geographically unrelated Indian population groups.PloS one · 2013
    Article

Corrections and comments

• Comment on
  Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians.2012

Authors and funding

1 author.

Funding

Abstract

PubMed holds no abstract for this paper.

Indexed as