Evidence map›Paper›PMID 22297509›Full record

ReviewAdvances in experimental medicine and biology2012

Principles of virus structural organization.

B V Venkataram Prasad, Michael F Schmid

Abstract readReview
In one paragraph

Review in Advances in experimental medicine and biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.

0numbers the graph read from it
0cells of the map it votes in
63citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

63 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. The Basic Architecture of Viruses.Sub-cellular biochemistry · 2024
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Review
  12. Review
  13. Capsid Structure ofJournal of virology · 2021
    Article
  14. Micro and Nanoscale Technologies for Diagnosis of Viral Infections.Small (Weinheim an der Bergstrasse, Germany) · 2021
    Review
  15. Viral Phrenology.Viruses · 2021
    Article
  16. Review
  17. Review
  18. Role of Phage Capsid in the Resistance to UV-C Radiations.International journal of molecular sciences · 2021
    Article
  19. Review
  20. Article

3 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

B V Venkataram PrasadDepartment of Biochemistry and Molecular Biology, Baylor College of Medicine, Houston, TX 77030, USA. vprasad@bcm.tmc.edu
Michael F Schmid

Funding

X-ray Crystallographic Studies on CalicivirusesP01AI057788 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI ATMAR, ROBERT L., ESTES, MARY KOLB · 2004 to 2024
$34.4M
Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI Geoffrey A Preidis · 2001 to 2026
$28.3M
ZERNIKE PHASE PLATE CRYOEM IN OKAZAKIP41RR002250 · NCRR · UNIVERSITY OF ARIZONA · PI CHIU, WAH · 1985 to 2011
$22.1M
X-RAY STUDY OF HORMONE-RECEPTOR AND PROTEIN-ANTIBODY COMPLEXESP41RR007707 · NCRR · UNIVERSITY OF CHICAGO · PI YANG, XIANGZHONG · 2002 to 2011
$17.3M
Structural Studies on RotavirusesR37AI036040 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI PRASAD, BIDADI VENKATARAM · 2003 to 2022
$10.9M
STRUCTURAL STUDIES ON ROTAVIRUSESR01AI036040 · NIAID · BAYLOR COLLEGE OF MEDICINE · PI Bidadi Venkataram Prasad · 1994 to 2026
$4.3M
NCRR NIH HHS P41 RR002250NCRR NIH HHS P41 RR007707NCRR NIH HHS P41RR02250NIAID NIH HHS P01 AI057788NIAID NIH HHS P01AI057788NIAID NIH HHS R01 AI036040NIAID NIH HHS R37 AI036040NIAID NIH HHS R37AI36040NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

Viruses, the molecular nanomachines infecting hosts ranging from prokaryotes to eukaryotes, come in different sizes, shapes, and symmetries. Questions such as what principles govern their structural organization, what factors guide their assembly, how these viruses integrate multifarious functions into one unique structure have enamored researchers for years. In the last five decades, following Caspar and Klug's elegant conceptualization of how viruses are constructed, high-resolution structural studies using X-ray crystallography and more recently cryo-EM techniques have provided a wealth of information on structures of a variety of viruses. These studies have significantly -furthered our understanding of the principles that underlie structural organization in viruses. Such an understanding has practical impact in providing a rational basis for the design and development of antiviral strategies. In this chapter, we review principles underlying capsid formation in a variety of viruses, emphasizing the recent developments along with some historical perspective.

Indexed as

AnimalsCapsidCapsid ProteinsCryoelectron MicroscopyCrystallography, X-RayHumansModels, MolecularProtein ConformationVirusesCapsid Proteins

Identifiers

PMID22297509
PMCPMC3767311

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.