ReviewNeurobiology of disease2013
Cell signaling and mitochondrial dynamics: Implications for neuronal function and neurodegenerative disease.
Review in Neurobiology of disease, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 66 citations in OpenAlex.
- Nrf2 Deficiency Exacerbates Methamphetamine-Induced Neuronal Apoptosis and Cognitive Dysfunction in Male Mice.International journal of molecular sciences · 2026Article
- Exposure to cigarette smoke during prenatal period alters the brain energy metabolism of rats subjected to an animal model of schizophrenia.Metabolic brain disease · 2026Article
- Article
- Effects of phosphorylation on Drp1 activation by its receptors, actin, and cardiolipin.Molecular biology of the cell · 2024Article
- Mitochondrial dynamics and its impact on human health and diseases: inside the DRP1 blackbox.Journal of molecular medicine (Berlin, Germany) · 2022Review
- Erythroid Differentiation and Heme Biosynthesis Are Dependent on a Shift in the Balance of Mitochondrial Fusion and Fission Dynamics.Frontiers in cell and developmental biology · 2020Article
- The phosphorylation status of Ser-637 in dynamin-related protein 1 (Drp1) does not determine Drp1 recruitment to mitochondria.The Journal of biological chemistry · 2019Article
- Interplay between NADBiochimica et biophysica acta. Molecular basis of disease · 2019Review
- MTP18 is a Novel Regulator of Mitochondrial Fission in CNS Neuron Development, Axonal Growth, and Injury Responses.Scientific reports · 2019Article
- Mitochondrial Morphofunction in Mammalian Cells.Antioxidants & redox signaling · 2019Review
- Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice.The Journal of clinical investigation · 2019Article
- Mdivi-1 Protects CD4Mediators of inflammation · 2019Article
- Nicotine Modulates Mitochondrial Dynamics in Hippocampal Neurons.Molecular neurobiology · 2018Article
- ROS as Regulators of Mitochondrial Dynamics in Neurons.Cellular and molecular neurobiology · 2018Review
- Reduction of the ATPase inhibitory factor 1 (IFCell death & disease · 2018Article
- Significance of Mitochondrial Protein Post-translational Modifications in Pathophysiology of Brain Injury.Translational stroke research · 2018Review
- Modulation of Mitochondrial Dynamics in Neurodegenerative Diseases: An Insight Into Prion Diseases.Frontiers in aging neuroscience · 2018Review
- Contribution of Tau Pathology to Mitochondrial Impairment in Neurodegeneration.Frontiers in neuroscience · 2018Review
- Connecting mitochondrial dynamics and life-or-death events via Bcl-2 family proteins.Neurochemistry international · 2017Review
- SUMOylation and calcium signalling: potential roles in the brain and beyond.Neuronal signaling · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Nascent evidence indicates that mitochondrial fission, fusion, and transport are subject to intricate regulatory mechanisms that intersect with both well-characterized and emerging signaling pathways. While it is well established that mutations in components of the mitochondrial fission/fusion machinery can cause neurological disorders, relatively little is known about upstream regulators of mitochondrial dynamics and their role in neurodegeneration. Here, we review posttranslational regulation of mitochondrial fission/fusion enzymes, with particular emphasis on dynamin-related protein 1 (Drp1), as well as outer mitochondrial signaling complexes involving protein kinases and phosphatases. We also review recent evidence that mitochondrial dynamics has profound consequences for neuronal development and synaptic transmission and discuss implications for clinical translation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.