Evidence map›Paper›PMID 22296197›Full record

ArticleBiomarkers in medicine2012

Cardiac myosin binding protein-C: a potential early-stage, cardiac-specific biomarker of ischemia-reperfusion injury.

Sakthivel Sadayappan

Abstract readEditorial
In one paragraph

Article in Biomarkers in medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Release kinetics of circulating cardiac myosin binding protein-C following cardiac injury.American journal of physiology. Heart and circulatory physiology · 2014
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sakthivel Sadayappan

Funding

Sarcomeric Modifications and Progressive Cardiac MaladaptationP01HL062426 · NHLBI · UNIVERSITY OF ILLINOIS AT CHICAGO · PI AI, XUN · 2000 to 2020
$42.4M
Fast myosin binding protein-C and cardiac contractility in heart failureR01HL105826 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2011 to 2025
$4.5M
Myosin Binding Protein C structure-function relationships in the failing heartP30HL101297 · NHLBI · LOYOLA UNIVERSITY CHICAGO · PI DE TOMBE, PIETER P. · 2009 to 2010
$703k
Proteomic approaches to validate novel cardiac biomarkers for myocardial infarctiK02HL114749 · NHLBI · UNIVERSITY OF CINCINNATI · PI SADAYAPPAN, SAKTHIVEL · 2012 to 2016
$498k
NHLBI NIH HHS 5P30HL101297NHLBI NIH HHS K02 HL114749NHLBI NIH HHS P01 HL062426NHLBI NIH HHS P30 HL101297NHLBI NIH HHS R01 HL105826NHLBI NIH HHS R01HL105826
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiomarkersCarrier ProteinsHumansMyocardiumMyosin Binding Protein COrgan SpecificityReperfusion InjuryTime FactorsBiomarkersCarrier ProteinsMyosin Binding Protein C

Identifiers

PMID22296197
PMCPMC3339268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.