Evidence map›Paper›PMID 22296183›Full record

ArticleJournal of anatomy2012

Gender-based differences in the shape of the human corpus callosum are associated with allometric variations.

Emiliano Bruner, José Manuel de la Cuétara, Roberto Colom, Manuel Martin-Loeches

Abstract read
In one paragraph

Article in Journal of anatomy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  7. Ethnicity Influences Corpus Callosum Dimensions.Neurology research international · 2018
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Emiliano BrunerCentro Nacional de Investigación sobre la Evolución Humana, Burgos, Spain. emiliano.bruner@cenieh.es
José Manuel de la Cuétara
Roberto Colom
Manuel Martin-Loeches

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The corpus callosum displays considerable morphological variability between individuals. Although some characteristics are thought to differ between male and female brains, there is no agreement regarding the source of this variation. Biomedical imaging and geometric morphometrics have provided tools to investigate shape and size variation in terms of integration and correlation. Here we analyze variations at the midsagittal outline of the corpus callosum in a sample of 102 young adults in order to describe and quantify the pattern of covariation associated with its morphology. Our results suggest that the shape of the corpus callosum is characterized by low levels of morphological integration, which explains the large variability. In larger brains, a minor allometric component involves a relative reduction of the splenium. Small differences between males and?females are associated with this allometric pattern, induced primarily by size variation rather than gender-specific characteristics.

Indexed as

Sex CharacteristicsAdolescentAdultCorpus CallosumFemaleHumansMagnetic Resonance ImagingMaleOrgan SizeYoung Adult

Identifiers

PMID22296183
PMCPMC3375777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.