ArticleInternational journal of breast cancer2011
Subgross morphology, the sick lobe hypothesis, and the success of breast conservation.
Article in International journal of breast cancer, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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Who cites it
9 citing papers in PubMed.
- Systematic assessment of HER2 status in ductal carcinoma in situ of the breast: a perspective on the potential clinical relevance.Breast cancer research : BCR · 2024Review
- A conditional inference tree model for predicting cancer risk of non-mass lesions detected on breast ultrasound.European radiology · 2024Article
- The subgross morphology of breast carcinomas: a single-institution series of 2033 consecutive cases documented in large-format histology slides.Virchows Archiv : an international journal of pathology · 2020Article
- Paradigm shift in the local treatment of breast cancer: mastectomy to breast conservation surgery.Gland surgery · 2018Review
- Preoperative imaging for breast conservation surgery-do we need more than conventional imaging for local disease assessment?Gland surgery · 2018Review
- Pathobiology of the 129:Stat1Breast cancer research : BCR · 2017Article
- Minimalist breast conserving surgical approaches for inferiorly sited cancers.Gland surgery · 2017Article
- Optimising Breast Conservation Treatment for Multifocal and Multicentric Breast Cancer: A Worthwhile Endeavour?World journal of surgery · 2016Article
- The role of large-format histopathology in assessing subgross morphological prognostic parameters: a single institution report of 1000 consecutive breast cancer cases.International journal of breast cancer · 2012Article
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Authors and funding
1 author.
Funding
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Abstract
Breast carcinoma has a complex subgross morphology in the majority of cases. The malignant transformation usually involves a single breast lobe and may demonstrate peripheral, segmental, or lobar growth patterns in the in situ phase. During the invasive phase, the tumor may grow beyond the borders of the affected lobe. The dimensions of the involved lobe and the pattern of its involvement determine the extent of the disease in the early phase, with the size, type, and position of the invasive foci being additional determinants in more advanced cases. Breast carcinomas of limited extent (occupying a tissue area <40 mm) are proper candidates for breast-conserving surgery. In other cases, careful individual preoperative assessment of disease extent is necessary in making decisions about the most appropriate surgical approach, taking into account the position of the lesion(s) within the breast, the dimensions of the breast, and patient preference.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.