ArticleThe Journal of manual & manipulative therapy2011
Clinical equipoise and personal equipoise: two necessary ingredients for reducing bias in manual therapy trials.
Article in The Journal of manual & manipulative therapy, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 96 citations in OpenAlex.
- Autonomic nervous system and endocrine system response to upper or lower cervical spine mobilization in males with persistent post-concussion symptoms: a proof-of-concept trial.The Journal of manual & manipulative therapy · 2024Trial
- Autonomic nervous system and endocrine system response to upper and lower cervical spine mobilization in healthy male adults: a randomized crossover trial.The Journal of manual & manipulative therapy · 2023Trial
- The acceptability of a guided internet-based trauma-focused self-help programme (Spring) for post-traumatic stress disorder (PTSD).European journal of psychotraumatology · 2023Trial
- Self-Guided Smartphone Application to Manage Chronic Musculoskeletal Pain: A Randomized, Controlled Pilot Trial.International journal of environmental research and public health · 2022Trial
- Trial
- Surgical treatments compared with early structured physiotherapy in secondary care for adults with primary frozen shoulder: the UK FROST three-arm RCT.Health technology assessment (Winchester, England) · 2020Trial
- Intellectual Equipoise and Challenges: Accruing Patients With Advanced Cancer to a Trial Randomizing to Surgical or Nonsurgical Management (SWOG S1316).The American journal of hospice & palliative care · 2020Trial
- Ethical Considerations and Equipoise in Cancer Surgery.Indian journal of surgical oncology · 2024Review
- Bayes' Theorem in Neurocritical Care: Principles and Practice.Neurocritical care · 2023Review
- Considerations for shared decision-making in treatment of chronic rhinosinusitis with nasal polyps.Frontiers in allergy · 2023Review
- Future applications of 3D bioprinting: A promising technology for treating recessive dystrophic epidermolysis bullosa.Experimental dermatology · 2022Article
- Identifying Ethical and Culturally Responsive Research Activities to Build Trust and Improve Participation of Black Sexual Minority Men in Pre-Exposure Prophylaxis Telehealth Clinical Trials: Qualitative Study.JMIR human factors · 2022Article
- Patient Willingness to Pay for Faster Return to Work or Smaller Incisions.Hand (New York, N.Y.) · 2021Article
- Lack of evidence for stating 'spinal source' of pain in EXPOSS study.The Journal of manual & manipulative therapy · 2020Article
- Post-randomization bias.The Journal of manual & manipulative therapy · 2020Article
- "And Then He Got into the Wrong Group": A Qualitative Study Exploring the Effects of Randomization in Recruitment to a Randomized Controlled Trial.International journal of environmental research and public health · 2020Article
- Optimising ambulance service contribution to clinical trials: a phenomenological exploration using focus groups.British paramedic journal · 2019Article
- Barriers and incentives to recruitment in mental health clinical trials.Evidence-based mental health · 2019Article
- Five good reasons to be disappointed with randomized trials.The Journal of manual & manipulative therapy · 2019Article
- The over-representation of significant p values in abstracts compared to corresponding full texts: A systematic review of surgical randomized trials.Contemporary clinical trials communications · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Clinical and personal equipoise exists when a clinician has no good basis for a choice between two or more care options or when one is truly uncertain about the overall benefit or harm offered by the treatment to his/her patient. For most manual therapy trials, equipoise does not likely exist. Because of the nature of the intervention a lack of equipoise can lead to bias and may account for a portion of the 'effect' that has traditionally been assigned to the intervention. Although there are methodological mechanisms to reduce the risk of bias associated with a lack of equipoise, most of the manual therapy trials to date are likely guilty of this form of bias.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.