ArticleSleep2012
Effects of a 3-hour sleep delay on sleep homeostasis in alcohol dependent adults.
Article in Sleep, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 37 citations in OpenAlex.
- Article
- Partial sleep deprivation with a 2-h time-in-bed may not change divergent thinking and insight problem solving in young males: a Bayesian analysis.Journal of physiological anthropology · 2026Article
- Sleep alterations in substance use disorders: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- The Beauty Sleep to Keep a Healthy Liver.International journal of molecular sciences · 2025Review
- Article
- Keep Your Mask On: The Benefits of Masking for Behavior and the Contributions of Aging and Disease on Dysfunctional Masking Pathways.Frontiers in neuroscience · 2022Review
- Sleep and alertness disturbance and substance use disorders: A bi-directional relation.Pharmacology, biochemistry, and behavior · 2021Review
- Current and potential pharmacological treatment options for insomnia in patients with alcohol use disorder in recovery.Neuropsychopharmacology reports · 2020Review
- Alcohol and sleep-related problems.Current opinion in psychology · 2019Review
- Effects of slow-wave activity on mood disturbance in major depressive disorder.Psychological medicine · 2019Article
- Neurophysiological correlates of suicidal ideation in major depressive disorder: Hyperarousal during sleep.Journal of affective disorders · 2017Article
- Sleep Disturbance in Substance Use Disorders.The Psychiatric clinics of North America · 2015Review
- Alcohol disrupts sleep homeostasis.Alcohol (Fayetteville, N.Y.) · 2015Review
- Cardiac autonomic function during sleep: effects of alcohol dependence and evidence of partial recovery with abstinence.Alcohol (Fayetteville, N.Y.) · 2015Article
- Article
- Sleep and substance use disorders: an update.Current psychiatry reports · 2014Review
- Poor autonomic nervous system functioning during sleep in recently detoxified alcohol-dependent men and women.Alcoholism, clinical and experimental research · 2014Article
- Chronic sleep restriction disrupts sleep homeostasis and behavioral sensitivity to alcohol by reducing the extracellular accumulation of adenosine.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Alcohol and the sleeping brain.Handbook of clinical neurology · 2014Review
- A preliminary study of slow-wave EEG activity and insulin sensitivity in adolescents.Sleep medicine · 2013Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
Abstract
objectivesThis study evaluated slow wave activity homeostatic response to a mild sleep challenge in alcohol-dependent adults compared to healthy controls.
designParticipants maintained a 23:00-06:00 schedule for 5 days verified by actigraphy and diary, followed by 3 nights in the lab: adaptation, baseline, and a sleep delay night with an 02:00-09:00 schedule.
settingSleep ' Chronophysiology laboratory.
participants48 alcohol-dependent adults (39 men, 9 women) who were abstinent for at least 3 weeks and 16 healthy control adults (13 men, 3 women), 21-55 years of age participated in study.
interventionsN/A. MEASUREMENTS AND
resultsSlow wave EEG activity (SWA) in consecutive NREM periods was compared between baseline and sleep delay nights and between AD and HC groups, using age and sex as statistical covariates. The AD group showed a blunted SWA response to sleep delay with significantly lower SWA power than the HC group. Exponential regression analyses confirmed lower asymptotic SWA with a slower decay rate over NREM sleep time in the AD group. Results were similar for raw SWA and %SWA on the delay night expressed relative to baseline SWA.
conclusionsAlcohol dependence is associated with impaired SWA regulation and a blunted response to a mild homeostatic sleep challenge.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.