Evidence map›Paper›PMID 22294757›Full record

SynthesisBMJ (Clinical research ed.)2012

Physical activity for cancer survivors: meta-analysis of randomised controlled trials.

Daniel Y T Fong, Judy W C Ho, Bryant P H Hui, Antoinette M Lee, Duncan J Macfarlane, Sharron S K Leung, Ester Cerin, Wynnie Y Y Chan, Ivy P F Leung, Sharon H S Lam and 2 more

8 registry-linked trialsOpen access · hybridAbstract readMeta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 8 registered trials, which are not on this map. Cited by 366 papers, 31 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
366citing papers in PubMed, 31 pooled it
82.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02439112 nacompletednot on this mapstarted 2015, after this paper: background citation

Early Initiated Individualized Physical Training in Newly Diagnosed Multiple Myeloma Patients; Effects on Physical Function, Physical Activity, Quality of Life, Pain, and Bone Disease.

TypeinterventionalSponsorZealand University HospitalRan2015 to 2020Enrolled102ConditionsMultiple MyelomaArmsExercise
NCT03482323 nacompletednot on this mapstarted 2018, after this paper: background citation

Improving Survival in Lung Cancer Patients: A Randomized Controlled Trial of Aerobic Exercise and Tai-chi Interventions

TypeinterventionalSponsorThe University of Hong KongRan2018 to 2019Enrolled30ConditionsLung Cancer PatientsArmsExercise, Tai-Chi
NCT03760653 nawithdrawnnot on this mapstarted 2018, after this paper: background citation

Physical Activity Along With a Probiotic for the Immune System and Quality of Life Improvement in Breast Cancer Survivor: A Randomised Controlled Pilot Study

TypeinterventionalSponsorUniversidad Europea de MadridRan2018 to 2019Enrolled0ConditionsBreast Cancer FemalesArmsPhysical Exercise and probiotic group, Probiotic group, Placebo group
NCT03883243 naunknown statusnot on this mapstarted 2019, after this paper: background citation

Monitoring and Telecoaching of Physical Activity in Patients With Stage III and IV Non-small Cell Lung Cancer

TypeinterventionalSponsorKU LeuvenRan2019 to 2020Enrolled32ConditionsExercise, NeoplasmsArmsTelecoaching
NCT04245657 completednot on this mapstarted 2019, after this paper: background citation

Investigation of the Factors of Hang-Grip Strength-related Upper Extremity Functionality After Breast Cancer Surgery

TypeobservationalSponsorIzmir Bakircay UniversityRan2019 to 2021Enrolled111ConditionsBreast Cancer, Breast Cancer Female, Breast Cancer Lymphedema, Breast Carcinoma in SituArmsTissue Dielectric Constant Measurement, Muscle strength measurement, Hand-Grip Strength Measurement, Pain Threshold Measurement, International Physical Activity Questionnaire-Short Form (IPAQ-SF)
NCT05349227 narecruitingnot on this mapstarted 2022, after this paper: background citation

Comprehensive Outcomes for After Cancer Health (COACH): the Feasibility and Impact of an MHealth Augmented Coaching Program for Self-Management in Cancer Survivors

TypeinterventionalSponsorPack HealthRan2022 to 2027Enrolled625ConditionsOvarian Cancer, Breast Cancer, Lung Cancer, Gastric CancerArmsDigital Health Coaching Program, Fitbit
NCT05375162 naactive not recruitingnot on this mapstarted 2023, after this paper: background citation

Optimization of a mHealth Physical Activity Promotion Intervention With Mindful Awareness for Adolescent and Young Adult Cancer Survivors

TypeinterventionalSponsorNorthwestern UniversityRan2023 to 2026Enrolled304ConditionsCancerArmsCore Intervention, E-Coach, General Mindfulness Training, MVPA-Specific Mindfulness Training, Buddy
NCT06435975 nacompletednot on this mapstarted 2022, after this paper: background citation

Pilot Study of Physical Activity Intervention to Manage Bowel Dysfunction in Rectal Cancer Survivors

TypeinterventionalSponsorAbramson Cancer Center at Penn MedicineRan2022 to 2024Enrolled20ConditionsRectal Cancer, Rectosigmoid CancerArmsPhysical Activity, Survey, Telehealth Lifestyle Coaching
3 · Its place in the literature

Who cites it

366 citing papers in PubMed, 31 syntheses or guidelines pooled it, 784 citations in OpenAlex.

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  8. Health-related quality of life in rural cancer survivors compared with their urban counterparts: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
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  11. Barriers and facilitators to physical activity in cancer survivors with pain: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
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  19. Cardiopulmonary Exercise Testing in Oesophagogastric Surgery: a Systematic Review.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2020
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306 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 3 countries.

Daniel Y T FongSchool of Nursing, Li Ka Shing Faculty of Medicine, University of Hong Kong, China.
Judy W C Ho
Bryant P H Hui
Antoinette M Lee
Duncan J Macfarlane
Sharron S K Leung
Ester Cerin
Wynnie Y Y Chan
Ivy P F Leung
Sharon H S Lam
Aliki J Taylor
Kar-keung Cheng
University of Hong Kong · HKUniversity of Birmingham · GBChinese University of Hong Kong · CNHong Kong Baptist University · HKHong Kong Polytechnic University · HKQueen Elizabeth Hospital · CNQueen Mary Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo systematically evaluate the effects of physical activity in adult patients after completion of main treatment related to cancer.

designMeta-analysis of randomised controlled trials with data extraction and quality assessment performed independently by two researchers. DATA SOURCES: Pubmed, CINAHL, and Google Scholar from the earliest possible year to September 2011. References from meta-analyses and reviews. STUDY SELECTION: Randomised controlled trials that assessed the effects of physical activity in adults who had completed their main cancer treatment, except hormonal treatment.

resultsThere were 34 randomised controlled trials, of which 22 (65%) focused on patients with breast cancer, and 48 outcomes in our meta-analysis. Twenty two studies assessed aerobic exercise, and four also included resistance or strength training. The median duration of physical activity was 13 weeks (range 3-60 weeks). Most control groups were considered sedentary or were assigned no exercise. Based on studies on patients with breast cancer, physical activity was associated with improvements in insulin-like growth factor-I, bench press, leg press, fatigue, depression, and quality of life. When we combined studies on different types of cancer, we found significant improvements in body mass index (BMI), body weight, peak oxygen consumption, peak power output, distance walked in six minutes, right handgrip strength, and quality of life. Sources of study heterogeneity included age, study quality, study size, and type and duration of physical activity. Publication bias did not alter our conclusions.

conclusionsPhysical activity has positive effects on physiology, body composition, physical functions, psychological outcomes, and quality of life in patients after treatment for breast cancer. When patients with cancer other than breast cancer were also included, physical activity was associated with reduced BMI and body weight, increased peak oxygen consumption and peak power output, and improved quality of life.

Indexed as

Quality of LifeAdultBody ConstitutionBreast NeoplasmsExerciseFatigueFemaleHumansMotor ActivityOutcome Assessment, Health CareRandomized Controlled Trials as TopicSurvivors

Identifiers

PMID22294757
PMCPMC3269661
OpenAlexW2084777875

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

and 2 more above

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.