ArticleThe Plant cell2012
Regulation of the photorespiratory GLDPA gene in C(4) flaveria: an intricate interplay of transcriptional and posttranscriptional processes.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Phenotypic landscape inference reveals multiple evolutionary paths to C4 photosynthesis.eLife · 2013Pooled it
- Synthetic Biology of Plants and Microbes for Agriculture, Environment, and Future Applications.Chemical reviews · 2026Review
- A transcription factor ensemble orchestrates bundle sheath expression in rice.Nature communications · 2025Article
- A transcription factor module mediating CEMBO reports · 2025Article
- Agrobacterium-mediated transient transformation of Flaveria bidentis leaves: a novel method to examine the evolution of CPlant methods · 2024Article
- A K homology (KH) domain protein identified by a forward genetic screen affects bundle sheath anatomy inPlant direct · 2024Article
- Compartmentation of photosynthesis gene expression in C4 maize depends on time of day.Plant physiology · 2023Article
- Photorespiration: regulation and new insights on the potential role of persulfidation.Journal of experimental botany · 2023Review
- A scheme for CPlant molecular biology · 2022Review
- Shedding light on AT1G29480 ofPlant direct · 2022Article
- OBV (obscure vein), a CHorticulture research · 2021Article
- Challenges and Approaches to Crop Improvement Through C3-to-C4 Engineering.Frontiers in plant science · 2021Review
- ZmOrphan94 Transcription Factor DownregulatesFrontiers in plant science · 2021Article
- A bipartite transcription factor module controlling expression in the bundle sheath of Arabidopsis thaliana.Nature plants · 2020Article
- Targeted misexpression of NAC052, acting in H3K4 demethylation, alters leaf morphological and anatomical traits in Arabidopsis thaliana.Journal of experimental botany · 2020Article
- Reporter-based forward genetic screen to identify bundle sheath anatomy mutants in A. thaliana.The Plant journal : for cell and molecular biology · 2019Article
- Expression of SULTR2;2, encoding a low-affinity sulphur transporter, in the Arabidopsis bundle sheath and vein cells is mediated by a positive regulator.Journal of experimental botany · 2018Article
- T-protein is present in large excess over the other proteins of the glycine cleavage system in leaves of Arabidopsis.Planta · 2018Article
- An Untranslated cis-Element Regulates the Accumulation of Multiple C4 Enzymes in Gynandropsis gynandra Mesophyll Cells.The Plant cell · 2016Article
- Endoreduplication is not involved in bundle-sheath formation in the C4 species Cleome gynandra.Journal of experimental botany · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The mitochondrial Gly decarboxylase complex (GDC) is a key component of the photorespiratory pathway that occurs in all photosynthetically active tissues of C(3) plants but is restricted to bundle sheath cells in C(4) species. GDC is also required for general cellular C(1) metabolism. In the Asteracean C(4) species Flaveria trinervia, a single functional GLDP gene, GLDPA, encodes the P-subunit of GDC, a decarboxylating Gly dehydrogenase. GLDPA promoter reporter gene fusion studies revealed that this promoter is active in bundle sheath cells and the vasculature of transgenic Flaveria bidentis (C(4)) and the Brassicacean C(3) species Arabidopsis thaliana, suggesting the existence of an evolutionarily conserved gene regulatory system in the bundle sheath. Here, we demonstrate that GLDPA gene regulation is achieved by an intricate interplay of transcriptional and posttranscriptional mechanisms. The GLDPA promoter is composed of two tandem promoters, P(R2) and P(R7), that together ensure a strong bundle sheath expression. While the proximal promoter (P(R7)) is active in the bundle sheath and vasculature, the distal promoter (P(R2)) drives uniform expression in all leaf chlorenchyma cells and the vasculature. An intron in the 5' untranslated leader of P(R2)-derived transcripts is inefficiently spliced and apparently suppresses the output of P(R2) by eliciting RNA decay.
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