ArticleThe Plant cell2012
Loss of abaxial leaf epicuticular wax in Medicago truncatula irg1/palm1 mutants results in reduced spore differentiation of anthracnose and nonhost rust pathogens.
Article in The Plant cell, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 54 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
54 citing papers in PubMed, 133 citations in OpenAlex.
- Pea Rust in Western Siberia: Resistant Varieties and Defense Mechanisms.Journal of fungi (Basel, Switzerland) · 2026Article
- Winning by Losing: Exploiting Modified Plant Susceptibility Genes to Counteract Necrotrophic Fungal Pathogens.Plant biotechnology journal · 2025Review
- Turning Susceptibility into Strength: A New Era of Durable Resistance in Plants Through Genome Editing.Plants (Basel, Switzerland) · 2025Review
- Comparative transcriptome analysis reveals the function of SoCER4 in alkanol synthesis in sugarcane.Functional & integrative genomics · 2025Article
- First line of defence: Eucalyptus leaf waxes influence infection by an aggressive fungal leaf pathogen.Plant biology (Stuttgart, Germany) · 2025Article
- Silencing of disease susceptibility genes: an effective disease resistance strategy against fungal pathogens.Plant cell reports · 2025Review
- What are the 100 most cited fungal genera?Studies in mycology · 2024Article
- Lipids and Lipid-Mediated Signaling in Plant-Pathogen Interactions.International journal of molecular sciences · 2024Review
- Genome engineering of disease susceptibility genes for enhancing resistance in plants.Functional & integrative genomics · 2023Review
- Cranberry fruit epicuticular wax benefits and identification of a wax-associated molecular marker.BMC plant biology · 2023Article
- Genetic approaches to dissect plant nonhost resistance mechanisms.Molecular plant pathology · 2023Review
- The Effects of Epicuticular Wax on Anthracnose Resistance ofInternational journal of molecular sciences · 2023Article
- A genome-wide association study and genomic prediction forFrontiers in plant science · 2023Article
- Ambivalent response in pathogen defense: A double-edged sword?Plant communications · 2022Review
- Receptor-mediated nonhost resistance in plants.Essays in biochemistry · 2022Review
- Article
- Research Progress and Prospect of Alfalfa Resistance to Pathogens and Pests.Plants (Basel, Switzerland) · 2022Review
- A Plant-Derived Alkanol Induces Teliospore Germination inJournal of fungi (Basel, Switzerland) · 2022Article
- Contrasting a reference cranberry genome to a crop wild relative provides insights into adaptation, domestication, and breeding.PloS one · 2022Article
- BnA1.CER4 and BnC1.CER4 are redundantly involved in branched primary alcohols in the cuticle wax of Brassica napus.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2021Article
Corrections and comments
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Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
To identify genes that confer nonhost resistance to biotrophic fungal pathogens, we did a forward-genetics screen using Medicago truncatula Tnt1 retrotransposon insertion lines. From this screen, we identified an inhibitor of rust germ tube differentation1 (irg1) mutant that failed to promote preinfection structure differentiation of two rust pathogens, Phakopsora pachyrhizi and Puccinia emaculata, and one anthracnose pathogen, Colletotrichum trifolii, on the abaxial leaf surface. Cytological and chemical analyses revealed that the inhibition of rust preinfection structures in irg1 mutants is due to complete loss of the abaxial epicuticular wax crystals and reduced surface hydrophobicity. The composition of waxes on abaxial leaf surface of irg1 mutants had >90% reduction of C30 primary alcohols and a preferential increase of C29 and C31 alkanes compared with the wild type. IRG1 encodes a Cys(2)His(2) zinc finger transcription factor, PALM1, which also controls dissected leaf morphology in M. truncatula. Transcriptome analysis of irg1/palm1 mutants revealed downregulation of eceriferum4, an enzyme implicated in primary alcohol biosynthesis, and MYB96, a major transcription factor that regulates wax biosynthesis. Our results demonstrate that PALM1 plays a role in regulating epicuticular wax metabolism and transport and that epicuticular wax influences spore differentiation of host and nonhost fungal pathogens.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.