Evidence map›Paper›PMID 22293871›Full record

ArticleMedical science monitor : international medical journal of experimental and clinical research2012

Lack of association of conjunctival MALT lymphoma with Chlamydiae or Helicobacter pylori in a cohort of Chinese patients.

Ji-Ping Cai, Jin-Wei Cheng, Xiao-Ye Ma, Yu-Zhen Li, You Li, Xiao Huang, Rui-Li Wei

Abstract read
In one paragraph

Article in Medical science monitor : international medical journal of experimental and clinical research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Involvement of Helicobacter Pylori in Ocular Adnexa Lymphoma.Pathology oncology research : POR · 2020
    Pooled it
  2. Infectious etiologies of conjunctival tumors.Expert review of ophthalmology · 2025
    Article
  3. Article
  4. Article
  5. Association between infection of virulence cagA gene Helicobacter pylori and laryngeal squamous cell carcinoma.Medical science monitor : international medical journal of experimental and clinical research · 2013
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ji-Ping CaiDepartment of Ophthalmology, Shanghai Changzheng Hospital, 2nd Military Medical University, Shanghai, China.
Jin-Wei Cheng
Xiao-Ye Ma
Yu-Zhen Li
You Li
Xiao Huang
Rui-Li Wei
Shanghai Changzheng Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThis study was conducted to detect microbial pathogens in conjunctival mucosa-associated lymphoid tissue (MALT) lymphoma specimens in an attempt to determine possible associations between conjunctival MALT lymphoma and microbial infections. MATERIAL/

methodsUsing PCR technique, freshly obtained tumor specimens from 16 cases of conjunctival MALT lymphoma, as confirmed by postoperative pathology, were analyzed for DNA of Chlamydia psittaci (C. psittaci), Chlamydia trachomatis (C. trachomatis), Chlamydia pneumoniae (C. pneumoniae) and Helicobacter pylori (H. pylori). Synthetic C. psittaci, C. trachomatis, C. pneumoniae and H. pylori DNA were used as positive control, and blank plasmid DNA as negative control.

resultsElectrophoresis showed that no bands corresponding to the positive control were observed in the specimens, indicating that no DNA of the 4 microorganisms was detected in the specimens of the 16 cases of conjunctival MALT lymphoma.

conclusionsThe PCR technique was able to detect the positive control quickly and accurately, but the results of PCR in analyzing the 16 specimens were negative, indicating that there is no association between conjunctival MALT lymphoma and the 4 microorganisms in Chinese patients.

Indexed as

Base SequenceChinaChlamydiaCohort StudiesConjunctival NeoplasmsDNA, BacterialDNA PrimersHelicobacter pyloriHumansLymphoma, B-Cell, Marginal ZonePolymerase Chain ReactionDNA, BacterialDNA Primers

Identifiers

PMID22293871
PMCPMC3560575
OpenAlexW2158483193

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.