Trial reportPloS one2012
Clinical pharmacists on medical care of pediatric inpatients: a single-center randomized controlled trial.
Trial report in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 9 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
38 citing papers in PubMed, 9 syntheses or guidelines pooled it, 73 citations in OpenAlex.
- Clinical and economic outcomes of hospital pharmaceutical care: a systematic review and meta-analysis.BMC health services research · 2020Pooled it
- The impact of the clinical pharmacist-led interventions in China: A systematic review and Meta-Analysis.International journal of clinical pharmacy · 2020Pooled it
- Pooled it
- Mapping the prevalence and nature of drug related problems among hospitalised children in the United Kingdom: a systematic review.BMC pediatrics · 2019Pooled it
- A systematic review of clinical pharmacist interventions in paediatric hospital patients.European journal of pediatrics · 2018Pooled it
- Do pharmacist-led medication reviews in hospitals help reduce hospital readmissions? A systematic review and meta-analysis.British journal of clinical pharmacology · 2016Pooled it
- Interventions for reducing medication errors in children in hospital.The Cochrane database of systematic reviews · 2015Pooled it
- Economic evaluations of clinical pharmacist interventions on hospital inpatients: a systematic review of recent literature.International journal of clinical pharmacy · 2014Pooled it
- Assessment of pharmacist-led patient counseling in randomized controlled trials: a systematic review.International journal of clinical pharmacy · 2014Pooled it
- Trial
- Polypharmacy and Drug Interaction Risk in Children and Adolescents with Congenital Heart Defects: Insights from a Nationwide Survey.Journal of clinical medicine · 2026Article
- The role and perception of the caregiver in a specialized pediatric palliative care center in medicine preparation and administration: a survey study.Italian journal of pediatrics · 2024Article
- Medicine education in a pediatric oncology setting: What can we do better?Exploratory research in clinical and social pharmacy · 2023Article
- The impact of pharmacists' interventions within the Closed Loop Medication Management process on medication safety: An analysis in a German university hospital.Frontiers in pharmacology · 2022Article
- Identification and solution of drug-related problems in the neurology unit of a tertiary hospital in China.BMC pharmacology & toxicology · 2021Article
- Optimizing Clinical Monitoring Tools to Enhance Patient Review by Pharmacists.Applied clinical informatics · 2021Article
- Pharmacist Prescribing in Pediatric and Neonatal Acute Care: An Observational Study.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2020Article
- Pharmacists in Critical Care.Innovations in pharmacy · 2019Article
- Interventions to reduce medication errors in neonatal care: a systematic review.Therapeutic advances in drug safety · 2018Review
- Service design oriented multidisciplinary collaborative team care service model development for resolving drug related problems.PloS one · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo explore the best interventions and working patterns of clinical pharmacists in pediatrics and to determine the effectiveness of clinical pharmacists in pediatrics.
methodsWe conducted a randomized controlled trial of 160 pediatric patients with nerve system disease, respiratory system disease or digestive system disease, who were randomly allocated into two groups, with 80 in each group. Interventions by clinical pharmacists in the experimental group included answering questions of physicians and nurses, giving advice on treating patients, checking prescriptions and patient counseling at discharge. In the control group, patients were treated without clinical pharmacist interventions.
resultsOf the 109 interventions provided by clinical pharmacists during 4 months, 47 were consultations for physicians and nurses, 31 were suggestions of treatment, with 30 accepted by physicians (96.77%) and 31 were medical errors found in 641 prescriptions. Five adverse drug reactions were submitted to the adverse drug reaction monitoring network, with three in the experimental group and two in the control group. The average length of stay (LOS) for patients with respiratory system diseases in the experimental group was 6.45 days, in comparison with 10.83 days in the control group, which was statistically different (p value<0.05); Average drug compliance rate in the experimental group was 81.41%, in comparison with 70.17% of the control group, which was statistically different (p value<0.05). Cost of drugs and hospitalization and rate of readmission in two weeks after discharge in the two groups were not statistically different.
conclusionParticipation by clinical pharmacists in the pharmacotherapy of pediatric patients can reduce LOS of patients with respiratory system disease and improve compliance rate through discharge education, showing no significant effects on prevention of ADR, reduction of cost of drugs and hospitalization and readmission rate in two weeks.
trial registrationChinese Clinical Trial Registry ChiCTR-TRC-10001081.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.