ArticlePloS one2012
Evidence for centromere drive in the holocentric chromosomes of Caenorhabditis.
Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 18 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 29 citations in OpenAlex.
- T2T genomes ofGenome research · 2026Article
- Recurrent but Short-Lived Duplications of Centromeric Proteins in Holocentric Caenorhabditis Species.Molecular biology and evolution · 2022Article
- The Centromere Histone Is Conserved and Associated with Tandem Repeats Sharing a Conserved 19-bp Box in the Holocentromere of Meloidogyne Nematodes.Molecular biology and evolution · 2021Article
- Holocentric Chromosomes Probably Do Not Prevent Centromere Drive in Cyperaceae.Frontiers in plant science · 2021Article
- Holocentric chromosomes.PLoS genetics · 2020Article
- Centromere Repeats: Hidden Gems of the Genome.Genes · 2019Review
- Transposable elements: genome innovation, chromosome diversity, and centromere conflict.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2018Review
- Satellite DNA: An Evolving Topic.Genes · 2017Review
- Centromeres Drive a Hard Bargain.Trends in genetics : TIG · 2017Review
- Absence of positive selection on CenH3 in Luzula suggests that holokinetic chromosomes may suppress centromere drive.Annals of botany · 2016Article
- To Break or Not To Break: Sex Chromosome Hemizygosity During Meiosis in Caenorhabditis.Genetics · 2016Article
- CenH3 evolution reflects meiotic symmetry as predicted by the centromere drive model.Scientific reports · 2016Article
- Flow cytometry may allow microscope-independent detection of holocentric chromosomes in plants.Scientific reports · 2016Article
- Co-evolving CENP-A and CAL1 Domains Mediate Centromeric CENP-A Deposition across Drosophila Species.Developmental cell · 2016Article
- Correction: Evidence for Centromere Drive in the Holocentric Chromosomes of Caenorhabditis.PloS one · 2016Article
- Centromeres Off the Hook: Massive Changes in Centromere Size and Structure Following Duplication of CenH3 Gene in Fabeae Species.Molecular biology and evolution · 2015Article
- Linkage map of the peppered moth, Biston betularia (Lepidoptera, Geometridae): a model of industrial melanism.Heredity · 2013Article
- Holocentric chromosomes: convergent evolution, meiotic adaptations, and genomic analysis.Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology · 2012Review
Corrections and comments
- Erratum issued
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In monocentric organisms with asymmetric meiosis, the kinetochore proteins, such as CENH3 and CENP-C, evolve adaptively to counterbalance the deleterious effects of centromere drive, which is caused by the expansion of centromeric satellite repeats. The selection regimes that act on CENH3 and CENP-C genes have not been analyzed in organisms with holocentric chromosomes, although holocentrism is speculated to have evolved to suppress centromere drive. We tested both CENH3 and CENP-C for positive selection in several species of the holocentric genus Caenorhabditis using the maximum likelihood approach and sliding-window analysis. Although CENP-C did not show any signs of positive selection, positive selection has been detected in the case of CENH3. These results support the hypothesis that centromere drive occurs in Nematoda, at least in the telokinetic meiosis of Caenorhabditis.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.