Evidence map›Paper›PMID 22291903›Full record

ArticlePloS one2012

Good glycemic control is associated with better survival in diabetic patients on peritoneal dialysis: a prospective observational study.

Dong Eun Yoo, Jung Tak Park, Hyung Jung Oh, Seung Jun Kim, Mi Jung Lee, Dong Ho Shin, Seung Hyeok Han, Tae-Hyun Yoo, Kyu Hun Choi, Shin-Wook Kang

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  6. Article
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  8. Flash glucose monitoring system in special situations.Archives of endocrinology and metabolism · 2022
    Review
  9. Article
  10. Review
  11. Observational
  12. Article
  13. Article
  14. The Current State of Peritoneal Dialysis.Journal of the American Society of Nephrology : JASN · 2016
    Review
  15. Article
  16. Article
  17. Glycemic control rate of T2DM outpatients in China: a multi-center survey.Medical science monitor : international medical journal of experimental and clinical research · 2015
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  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Dong Eun YooDepartment of Internal Medicine, College of Medicine, Brain Korea 21 for Medical Science, Severance Biomedical Science Institute, Yonsei University, Seoul, Korea.
Jung Tak Park
Hyung Jung Oh
Seung Jun Kim
Mi Jung Lee
Dong Ho Shin
Seung Hyeok Han
Tae-Hyun Yoo
Kyu Hun Choi
Shin-Wook Kang
Yonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe effect of glycemic control after starting peritoneal dialysis (PD) on the survival of diabetic PD patients has largely been unexplored, especially in Asian population.

methodsWe conducted a prospective observational study, in which 140 incident PD patients with diabetes were recruited. Patients were divided into tertiles according to the means of quarterly HbA1C levels measured during the first year after starting PD. We examined the association between HbA1C and all-cause mortality using Cox proportional hazards models.

resultsThe mean age was 58.7 years, 59.3% were male, and the mean follow-up duration was 3.5 years (range 0.4-9.5 years). The mean HbA1C levels were 6.3%, 7.1%, and 8.5% in the 1(st), 2(nd), and 3(rd) tertiles, respectively. Compared to the 1(st) tertile, the all-cause mortality rates were higher in the 2(nd) [hazard ratio (HR), 4.16; 95% confidence interval (CI), 0.91-18.94; p = 0.065] and significantly higher in the 3(rd) (HR, 13.16; 95% CI, 2.67-64.92; p = 0.002) tertiles (p for trend = 0.005), after adjusting for confounding factors. Cardiovascular mortality, however, did not differ significantly among the tertiles (p for trend = 0.682). In contrast, non-cardiovascular deaths, most of which were caused by infection, were more frequent in the 2(nd) (HR, 7.67; 95% CI, 0.68-86.37; p = 0.099) and the 3(rd) (HR, 51.24; 95% CI, 3.85-681.35; p = 0.003) tertiles than the 1(st) tertile (p for trend = 0.007).

conclusionsPoor glycemic control is associated with high mortality rates in diabetic PD patients, suggesting that better glycemic control may improve the outcomes of these patients.

Indexed as

Peritoneal DialysisAgedBlood GlucoseCause of DeathDiabetes Mellitus, Type 2Diabetic NephropathiesFemaleFollow-Up StudiesGlycated HemoglobinHumansKidney Failure, ChronicMaleMiddle AgedObservationProspective StudiesBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, human

Identifiers

PMID22291903
PMCPMC3264549
OpenAlexW1988615218

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.