ArticleArchives of medical science : AMS2011
The role of the immuno-inflammatory response in patients after cardiac arrest.
Article in Archives of medical science : AMS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 40 citations in OpenAlex.
- The association between C-reactive protein to albumin ratio and 6-month neurological outcome in patients with in-hospital cardiac arrest.World journal of emergency medicine · 2024Article
- Article
- Biomarkers associated with mortality in pediatric patients with cardiac arrest and acute respiratory distress syndrome.Resuscitation · 2022Article
- Prognostic value of the delta neutrophil index in pediatric cardiac arrest.Scientific reports · 2020Article
- Neutrophil-lymphocyte ratio: A prognostic tool in patients with in-hospital cardiac arrest.World journal of critical care medicine · 2019Article
- Endotoxemia induces lung-brain coupling and multi-organ injury following cerebral ischemia-reperfusion.Experimental neurology · 2017Article
- Systemic impact on secondary brain aggravation due to ischemia/reperfusion injury in post-cardiac arrest syndrome: a prospective observational study using high-mobility group box 1 protein.Critical care (London, England) · 2017Observational
- Intranasal post-cardiac arrest treatment with orexin-A facilitates arousal from coma and ameliorates neuroinflammation.PloS one · 2017Article
- History and current use of mild therapeutic hypothermia after cardiac arrest.Archives of medical science : AMS · 2016Article
- High Serum Tumor Necrosis Factor Levels in the Early Post-Cardiac Arrest Period Are Associated with Poor Short-Term Survival in a Swine Model of Ventricular Fibrillation.Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research · 2016Article
- Predicting the outcomes for out-of-hospital cardiac arrest patients using multiple biomarkers and suspension microarray assays.Scientific reports · 2016Article
- Mild hypothermia inhibits systemic and cerebral complement activation in a swine model of cardiac arrest.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2015Article
- Shock duration after resuscitation is associated with occurrence of post-cardiac arrest acute kidney injury.Journal of Korean medical science · 2015Observational
- Early activation of the kynurenine pathway predicts early death and long-term outcome in patients resuscitated from out-of-hospital cardiac arrest.Journal of the American Heart Association · 2014Observational
- Sublingual microcirculation is impaired in post-cardiac arrest patients.Resuscitation · 2013Article
- Article
- Serum C-reactive protein as a possible marker to predict delayed hemorrhage after colonoscopic polypectomy.Medical science monitor : international medical journal of experimental and clinical research · 2012Article
- The role of the immunoinflammatory response after cardiac arrest.Archives of medical science : AMS · 2011Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionThe aim of the research was to assess whether concentrations of inflammatory markers in blood of patients after cardiac arrest (CA) are related to their clinical state and survival. MATERIAL AND
methodsForty-six patients, aged 63 ±12 years, 21 of them after out-of-hospital CA and 25 after in-hospital CA, were enrolled in the study. Twenty-five patients survived and were discharged from hospital (CA-S); 21 died during hospitalization (CA-D). The clinical state of the patients was evaluated by the Glasgow Coma Scale (GCS) and the Acute Physiology and Chronic Health Evaluation II (APACHE II). On the day immediately after CA (day 1) and on the following day (day 2) the plasma concentration of high specific C-reactive protein (hs-CRP), tumour necrosis factor (TNF)-α, interleukin-10 and interleukin-6 (Ile-6) were measured.
resultsIn CA-D patients, compared with CA-S, a significantly higher concentration of hs-CRP (on day 1, 19 ±5 vs. 15 ±4; on day 2, 21 ±3 vs. 16 ±5 mg/l, p < 0.001) and Ile-6 (on day 1, 24.9 ±19.8 vs. 9.2 ±11.3; on day 2, 24.2 ±19.7 vs. 6.9 ±6.8 IU/ml, p < 0.001) was found. The level of TNF-α was greater in CA-D on day 1 (0.42 ±0.75 vs. 0.18 ±0.21 IU/ml, p < 0.04). Concentrations of hs-CRP and Ile-6 were correlated with the scores of GCS and APACHE II. Using logistic regression analysis and ROC curves the prognostic value of hs-CRP and Ile-6 for survival was proven.
conclusionsPost-cardiac arrest immuno-inflammatory response, reflected mainly in elevated plasma concentration of hs-CRP and Ile-6, is not only correlated with patients' clinical state but also with prediction of survival.
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