ArticleAntimicrobial agents and chemotherapy2012
Low cefepime concentrations during high blood and dialysate flow continuous venovenous hemodialysis.
Article in Antimicrobial agents and chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
6 citing papers in PubMed.
- Article
- Article
- Treatment of Acute Kidney Injury: A Review of Current Approaches and Emerging Innovations.Journal of clinical medicine · 2024Review
- Cefepime Extraction by Extracorporeal Life Support Circuits.The journal of extra-corporeal technology · 2022Article
- Cefepime Pharmacokinetics in Critically Ill Pediatric Patients Receiving Continuous Renal Replacement Therapy.Antimicrobial agents and chemotherapy · 2019Article
- Clinical implications of antibiotic pharmacokinetic principles in the critically ill.Intensive care medicine · 2013Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Dosing of cefepime during high blood flow (Qb; 300 ml/min), high dialysate flow (Qd; 3 liter/h) continuous venovenous hemodialysis (CVVHD) is undefined. Six patients on CVVHD had serum and effluent cefepime concentrations measured at 0.5, 1, 2, 6, and 12 h after dosing. Three patients had cefepime concentrations less than the MIC for Pseudomonas aeruginosa. A dose of 2,000 mg every 12 h or 1,000 mg every 8 h may increase time at a therapeutic concentration.
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Registered trials
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