Evidence map›Paper›PMID 22290342›Full record

Trial reportDigestive diseases and sciences2012

Comprehensive self-management reduces the negative impact of irritable bowel syndrome symptoms on sexual functioning.

Margaret D Eugenio, Sang-Eun Jun, Kevin C Cain, Monica E Jarrett, Margaret M Heitkemper

Registry-linked trialOpen access · greenAbstract readComparative StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04716738 (Sexual Dysfunction, Quality of Life and Visceral Hyperalgesia in Women With Irritable Bowel Syndrome), which is not on this map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04716738 unknown statusnot on this mapstarted 2023, after this paper: background citation

Sexual Dysfunction, Quality of Life and Visceral Hyperalgesia in Women With Irritable Bowel Syndrome

Typeobservational_patient_registrySponsorHospital General de MexicoRan2023 to 2023Enrolled20ConditionsIrritable Bowel Syndrome, Sexual DysfunctionArmsBlood analyses and coprological
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Margaret D EugenioDepartment of Internal Medicine, Division of Gastroenterology, School of Medicine, University of Washington, Seattle, WA 98195-6424, USA. margarete@medicine.washington.edu
Sang-Eun Jun
Kevin C Cain
Monica E Jarrett
Margaret M Heitkemper
University of Washington · USKeimyung University · KRNeurobehavioral Systems · US

Funding

NURSING MANAGEMENT OF IBS--IMPROVING OUTCOMESR01NR004142 · NINR · UNIVERSITY OF WASHINGTON · PI HEITKEMPER, MARGARET MCLEAN · 1996 to 2011
$5.5M
NURSING STUDY OF GUT FUNCTION IN MENSTRUATING WOMENR01NR001094 · NINR · UNIVERSITY OF WASHINGTON · PI HEITKEMPER, MARGARET MCLEAN · 1986 to 2013
$5.3M
Partnership CoreP30NR004001 · NINR · UNIVERSITY OF WASHINGTON · PI HEITKEMPER, MARGARET MCLEAN · 1994 to 2008
$3.7M
NINR NIH HHS P30 NR004001NINR NIH HHS P30 NR04001NINR NIH HHS R01 NR001094NINR NIH HHS R01 NR004142
6 · The paper itself

Abstract

backgroundWomen with irritable bowel syndrome (IBS) report sexual dysfunction. Comprehensive self-management (CSM) intervention has been shown to reduce gastrointestinal, psychological, and somatic symptoms in IBS women. Whether this intervention also reduces sexual dysfunction is not known.

aimsWe sought to compare demographic and clinical factors in IBS women with and without sexual dysfunction as defined by the Arizona sexual experiences scale (ASEX) and to test the effects of CSM treatment on sexual dysfunction scores and on the sexual relations subscale of an IBS quality of life (IBSQOL) scale which measures the effect of IBS on sexual QOL.

methodsIBS (Rome II) women enrolled in a randomized clinical trial of CSM treatment were characterized as having sexual dysfunction (N = 89) or not (N = 86) at baseline based on ASEX criteria. Baseline characteristics and symptoms were compared between the two groups. Post-intervention changes were compared between the CSM and the usual care arms of the randomized trial.

resultsWomen meeting ASEX criteria for sexual dysfunction were older, had higher lifetime depression and antidepressant use, more primary care/MD visits, fewer mental healthcare visits, and greater sleep disturbance than those without sexual dysfunction. No significant group differences in gastrointestinal or somatic symptoms were observed. Compared with usual care treatment, CSM increased sexual QOL scores and had a weaker effect on ASEX scores.

conclusionsSeverity of IBS symptoms at baseline did not differ between IBS women with or without sexual dysfunction. The CSM intervention can reduce the effect of IBS on sexual QOL.

Indexed as

Quality of LifeAdultFemaleFollow-Up StudiesHumansIrritable Bowel SyndromeMiddle AgedPatient Education as TopicReference ValuesRisk AssessmentSelf CareSexual Dysfunctions, PsychologicalSickness Impact ProfileStress, PsychologicalTreatment Outcome

Identifiers

PMID22290342
PMCPMC3694807
OpenAlexW2040586457

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.