Evidence map›Paper›PMID 22289420›Full record

ArticleJournal of biomedical informatics2012

A hybrid knowledge-based and data-driven approach to identifying semantically similar concepts.

Rimma Pivovarov, Noémie Elhadad

Abstract read
In one paragraph

Article in Journal of biomedical informatics, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Medication-indication knowledge bases: a systematic review and critical appraisal.Journal of the American Medical Informatics Association : JAMIA · 2015
    Pooled it
  2. Review
  3. Hierarchical Information Criterion for Variable Abstraction.Proceedings of machine learning research · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Automated methods for the summarization of electronic health records.Journal of the American Medical Informatics Association : JAMIA · 2015
    Review
  11. Article
  12. Article
  13. Article
  14. U-path: An undirected path-based measure of semantic similarity.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2014
    Article
  15. Article
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Rimma PivovarovDepartment of Biomedical Informatics, Columbia University, 622 W. 168th Street, VC-5, New York, NY 10032, USA.
Noémie Elhadad

Funding

Training in Biomedical Informatics at Columbia UniversityT15LM007079 · NLM · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI NOEMIE ELHADAD, GEORGE M HRIPCSAK · 1992 to 2026
$28.9M
An NLP Approach to Generating Patient Record SummariesR01LM010027 · NLM · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ELHADAD, NOEMIE · 2009 to 2010
$912k
NLM NIH HHS 5T15LM007079-19NLM NIH HHS HHSN276201000024CNLM NIH HHS R01 LM010027NLM NIH HHS T15 LM007079
6 · The paper itself

Abstract

An open research question when leveraging ontological knowledge is when to treat different concepts separately from each other and when to aggregate them. For instance, concepts for the terms "paroxysmal cough" and "nocturnal cough" might be aggregated in a kidney disease study, but should be left separate in a pneumonia study. Determining whether two concepts are similar enough to be aggregated can help build better datasets for data mining purposes and avoid signal dilution. Quantifying the similarity among concepts is a difficult task, however, in part because such similarity is context-dependent. We propose a comprehensive method, which computes a similarity score for a concept pair by combining data-driven and ontology-driven knowledge. We demonstrate our method on concepts from SNOMED-CT and on a corpus of clinical notes of patients with chronic kidney disease. By combining information from usage patterns in clinical notes and from ontological structure, the method can prune out concepts that are simply related from those which are semantically similar. When evaluated against a list of concept pairs annotated for similarity, our method reaches an AUC (area under the curve) of 92%.

Indexed as

Knowledge BasesSemanticsArea Under CurveChronic DiseaseData MiningHumansKidney DiseasesNatural Language ProcessingSystematized Nomenclature of Medicine

Identifiers

PMID22289420
PMCPMC3345313

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.