Evidence map›Paper›PMID 22288906›Full record

Trial reportJournal of abnormal psychology2012

Maternal cognitions and mother-infant interaction in postnatal depression and generalized anxiety disorder.

Alan Stein, Michelle G Craske, Annukka Lehtonen, Allison Harvey, Emily Savage-McGlynn, Beverley Davies, Julia Goodwin, Lynne Murray, Mario Cortina-Borja, Nicholas Counsell

Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of abnormal psychology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03351465 (A Randomized Controlled Trial of Coordinated Anxiety Learning and Management), which is not on this map. Cited by 78 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed, 4 pooled it
15.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03351465 nawithdrawnnot on this mapstarted 2020, after this paper: background citation

A Randomized Controlled Trial of Coordinated Anxiety Learning and Management (CALM) for Pregnant and Postpartum Women

TypeinterventionalSponsorUniversity of California, Los AngelesRan2020 to 2020Enrolled0ConditionsAnxiety, Depression, Depression, Postpartum, Pregnancy RelatedArmsCoordinated Anxiety Learning and Management
3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 4 syntheses or guidelines pooled it, 238 citations in OpenAlex.

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18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Alan SteinDepartment of Psychiatry, Warneford Hospital, University of Oxford, Oxford, United Kingdom. alan.stein@psych.ox.ac.uk
Michelle G Craske
Annukka Lehtonen
Allison Harvey
Emily Savage-McGlynn
Beverley Davies
Julia Goodwin
Lynne Murray
Mario Cortina-Borja
Nicholas Counsell
Warneford Hospital · GBUniversity College London · GBUniversity of California, Berkeley · USUniversity of California, Los Angeles · USUniversity of Reading · GB

Funding

Wellcome Trust 071571
6 · The paper itself

Abstract

Postnatal depression and anxiety have been shown to increase the risk of disturbances in mother-child interaction and child development. Research into mechanisms has focused on genetics and maternal behavior; maternal cognitions have received little attention. Our aim was to experimentally determine if worry and rumination in mothers with generalized anxiety disorder (GAD) and major depressive disorder (MDD), diagnosed in the postnatal 6 months, interfered with maternal responsiveness to their 10-month old infants. Mothers (N = 253: GAD n = 90; MDD n = 57; control n = 106) and their infants were randomized to either a worry/rumination prime (WRP) or a neutral prime (NP); mother-infant interactions were assessed before and after priming. Type of priming was a significant predictor of maternal cognitions, with WRP resulting in more negative thoughts, higher thought recurrence and more self-focus relative to NP across the entire sample. Interaction effects between group and priming were significant for two parenting variables: Compared with controls, WRP had a more negative impact on maternal responsiveness to infant vocalization for GAD, and to a lesser extent for MDD; WRP led to decreased maternal vocalization for GAD. Also, mothers with GAD used stronger control after the NP than WRP, as well as compared with other groups, and overall post-priming, their children exhibited lower emotional tone and more withdrawal. Across the entire sample, WRP was associated with increased child vocalization relative to NP. This study demonstrated that disturbances in maternal cognitions, in the context of postnatal anxiety and to a lesser degree depression, play a significant role in mother-child interaction.

Indexed as

CognitionMother-Child RelationsAdultAnxietyAnxiety DisordersAttentionDepressionDepression, PostpartumFemaleHumansInfantLongitudinal StudiesMaleMaternal BehaviorMothersParenting

Identifiers

PMID22288906
PMCPMC3506203
OpenAlexW2078419134

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.