Evidence map›Paper›PMID 22287982›Full record

ArticleImaging in medicine2011

Tracking stem cells for cardiovascular applications in vivo: focus on imaging techniques.

Yingli Fu, Nicole Azene, Yi Xu, Dara L Kraitchman

Abstract read
In one paragraph

Article in Imaging in medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Cell Therapy in the Treatment of Coronary Heart Disease.International journal of molecular sciences · 2023
    Review
  2. Review
  3. Quantitative CT andMagma (New York, N.Y.) · 2019
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yingli FuRussell H Morgan Department of Radiology & Radiological Science, Johns Hopkins University, Baltimore, MD, USA.
Nicole Azene
Yi Xu
Dara L Kraitchman

Funding

X-ray & MR-visible Microencapsulation of Allogeneic Arteriogenic Cell TherapeuticR33HL089029 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KRAITCHMAN, DARA L · 2009 to 2011
$2.1M
X-ray & MR-visible Microencapsulation of Allogeneic Arteriogenic Cell TherapeuticR21HL089029 · NHLBI · JOHNS HOPKINS UNIVERSITY · PI KRAITCHMAN, DARA L · 2007 to 2008
$814k
NHLBI NIH HHS R21 HL089029NHLBI NIH HHS R33 HL089029
6 · The paper itself

Abstract

Despite rapid translation of stem cell therapy into clinical practice, the treatment of cardiovascular disease using embryonic stem cells, adult stem and progenitor cells or induced pluripotent stem cells has not yielded satisfactory results to date. Noninvasive stem cell imaging techniques could provide greater insight into not only the therapeutic benefit, but also the fundamental mechanisms underlying stem cell fate, migration, survival and engraftment in vivo. This information could also assist in the appropriate choice of stem cell type(s), delivery routes and dosing regimes in clinical cardiovascular stem cell trials. Multiple imaging modalities, such as MRI, PET, SPECT and CT, have emerged, offering the ability to localize, monitor and track stem cells in vivo. This article discusses stem cell labeling approaches and highlights the latest cardiac stem cell imaging techniques that may help clinicians, research scientists or other healthcare professionals select the best cellular therapeutics for cardiovascular disease management.

Identifiers

PMID22287982
PMCPMC3265127

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.