ArticleHuman brain mapping2013
Functional architecture of the cortico-basal ganglia circuitry during motor task execution: correlations of strength of functional connectivity with neuropsychological task performance among female subjects.
Article in Human brain mapping, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Critical review of the evidence for Vojta Therapy: a systematic review and meta-analysis.Frontiers in neurology · 2024Pooled it
- Graph Theoretical Analysis of Brain Network Characteristics in Brain Tumor Patients: A Systematic Review.Neuropsychology review · 2022Pooled it
- Deep brain stimulation of the subthalamic nucleus, but not dopaminergic medication, improves proactive inhibitory control of movement initiation in Parkinson's disease.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2013Trial
- Intrinsic connectivity patterns of striatal subfields predict individual dimensions of psychopathology and are associated with cholinergic and serotonergic neurotransmission in schizophrenia.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026Article
- Different Brain Network Connectomic Relationships Subserve Hand Dexterity During Task Versus Resting States in People with Brain Tumors.Brain and behavior · 2025Article
- Whole Brain Monosynaptic Input of Distinct Neurons in the Globus Pallidus Externa.CNS neuroscience & therapeutics · 2025Article
- Immediate effects of Vojta Therapy on gait ability in down syndrome patients: a pilot study.Frontiers in neurology · 2024Article
- Joint Multi-modal Parcellation of the Human Striatum: Functions and Clinical Relevance.Neuroscience bulletin · 2020Article
- Neural Efficiency and Acquired Motor Skills: An fMRI Study of Expert Athletes.Frontiers in psychology · 2019Article
- The contribution of verbalization to action.Psychological research · 2015Article
- The subcortical cocktail problem; mixed signals from the subthalamic nucleus and substantia nigra.PloS one · 2015Article
- Auditory rhythmic cueing in movement rehabilitation: findings and possible mechanisms.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2014Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The primary aim of this study was to enhance our understanding of the functional architecture of the cortico-basal ganglia circuitry during motor task execution. Twenty right-handed female subjects without any history of neuropsychiatric illness underwent fMRI at 3 T. The activation paradigm was a complex motor task completed with the nondominant hand. Analyses of functional connectivity strength were conducted for pairs of structures in input, intrinsic, and output segments of the circuitry. Next, connectivity strengths were correlated with results of neurocognitive testing conducted outside of the scanner, which provided information about both motor and cognitive processes. For input pathways, results indicate that SMA-striatum interactions are particularly relevant for motor behavior and disruptions may impact both motor and cognitive functions. For intrinsic pathways, results indicate that thalamus (VA nucleus) to striatum feedback pathway appears to have an important role during task execution and carries information relevant for motor planning. Together, these findings add to accumulating evidence that the GPe may play a role in higher order basal ganglia processing. A potentially controversial finding was that strong functional connectivity appears to occur across intrinsic inhibitory pathways. Finally, output (thalamus to cortex) feedback was only correlated with motor planning. This result suggests circuit processes may be more relevant for future behaviors than the execution of the current task.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.