Evidence map›Paper›PMID 22287003›Full record

ArticleApplied and environmental microbiology2012

The histone-like nucleoid structuring protein (H-NS) is a repressor of Vibrio cholerae exopolysaccharide biosynthesis (vps) genes.

Hongxia Wang, Julio C Ayala, Anisia J Silva, Jorge A Benitez

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Non-O1/Non-O139Microorganisms · 2024
    Review
  4. Article
  5. Article
  6. Cholera Dynamics and the Emergence of Pandemic Vibrio cholerae.Advances in experimental medicine and biology · 2023
    Article
  7. Genome-wide transposon mutagenesis analysis ofFrontiers in cellular and infection microbiology · 2022
    Article
  8. Article
  9. On or Off: Life-Changing Decisions Made byInfectious microbes & diseases · 2020
    Review
  10. Motility of Vibrio spp.: regulation and controlling strategies.Applied microbiology and biotechnology · 2020
    Review
  11. Article
  12. Article
  13. Fur RepressesFrontiers in microbiology · 2020
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. NPJ biofilms and microbiomes · 2018
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hongxia WangSouthern Research Institute, Drug Discovery Division, Department of Biochemistry and Molecular Biology, Birmingham, Alabama, USA.
Julio C Ayala
Anisia J Silva
Jorge A Benitez

Funding

Vascular Cell Apoptosis: Mediator Role of Transforming Growth Factor-beta-1S06GM008248 · NIGMS · MOREHOUSE SCHOOL OF MEDICINE · PI SILVA, ANISIA J · 1989 to 2009
$19.8M
Regulation of Vibrio cholerae motility, stress response and detachment from intesSC1AI104993 · NIAID · MOREHOUSE SCHOOL OF MEDICINE · PI SILVA-BENITEZ, ANISIA J · 2012 to 2015
$1.3M
Regulation of the Vibrio cholerae intestinal exit planR21AI081039 · NIAID · MOREHOUSE SCHOOL OF MEDICINE · PI SILVA-BENITEZ, ANISIA J · 2009 to 2010
$385k
NIAID NIH HHS AI081039NIAID NIH HHS R21 AI081039NIAID NIH HHS SC1 AI104993NIGMS NIH HHS GM008248NIGMS NIH HHS S06 GM008248
6 · The paper itself

Abstract

The capacity of Vibrio cholerae to form biofilms has been shown to enhance its survival in the aquatic environment and play important roles in pathogenesis and disease transmission. In this study, we demonstrated that the histone-like nucleoid structuring protein is a repressor of exopolysaccharide (vps) biosynthesis genes and biofilm formation.

Indexed as

Bacterial ProteinsBiofilmsCulture MediaDNA-Binding ProteinsDown-RegulationGene Expression Regulation, BacterialHumansPolysaccharides, BacterialVibrio choleraeBacterial ProteinsCulture MediaDNA-Binding ProteinsH-NS protein, bacteriaPolysaccharides, Bacterial

Identifiers

PMID22287003
PMCPMC3302599

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.