Evidence map›Paper›PMID 22286984›Full record

ArticleApplied and environmental microbiology2012

Functional cloning and characterization of antibiotic resistance genes from the chicken gut microbiome.

Wei Zhou, Ying Wang, Jun Lin

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Article
  2. Review
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  15. Review
  16. FARME DB: a functional antibiotic resistance element database.Database : the journal of biological databases and curation · 2017
    Article
  17. Article
  18. Article
  19. Bloom of resident antibiotic-resistant bacteria in soil following manure fertilization.Proceedings of the National Academy of Sciences of the United States of America · 2014
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Wei ZhouDepartment of Animal Science, The University of Tennessee, Knoxville, Tennessee, USA.
Ying Wang
Jun Lin

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Culture-independent sampling in conjunction with a functional cloning approach identified diverse antibiotic resistance genes for different classes of antibiotics in gut microbiomes from both conventionally raised and free-range chickens. Many of the genes are phylogenetically distant from known resistance genes. Two unique genes that conferred ampicillin and spectinomycin resistance were also functional in Campylobacter, a distant relative of the Escherichia coli host used to generate the genomic libraries.

Indexed as

Cloning, MolecularDrug Resistance, BacterialGenes, BacterialAnimalsBacteriaChickensDNA, BacterialGastrointestinal TractGenetic VariationMicrobial Sensitivity TestsMolecular Sequence DataSequence Analysis, DNADNA, Bacterial

Identifiers

PMID22286984
PMCPMC3318844

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.