ArticlePathology oncology research : POR2012
D-dimer as a potential prognostic marker.
Article in Pathology oncology research : POR, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic Value of Pretreatment D-Dimer Level in Small-Cell Lung Cancer: A Meta-Analysis.Technology in cancer research & treatmentPooled it
- Preoperative high level of D-dimers predicts unresectability of pancreatic head cancer.World journal of gastroenterology · 2014Trial
- A multicenter retrospective study of plasma d‑dimer levels for evaluating treatment response in multiple myeloma.Scientific reports · 2026Article
- Development and validation of a nomogram for predicting pulmonary embolism in patients with pulmonary tuberculosis.Journal of thoracic disease · 2025Article
- Evaluation of treatment for diffuse large B-cell lymphoma using plasma D-dimer levels.Scientific reports · 2025Article
- Research progress on the association between lung cancer and pulmonary embolism.Journal of cardiothoracic surgery · 2025Review
- Diagnostic Value of Serum D-dimer, CA19-9, and CT Imaging Features in Pancreatic Ductal Adenocarcinoma and Benign Pancreatic Lesions.Journal of Cancer · 2025Article
- Values of a novel comprehensive prognostic nutritional index (FIDA) in the prognosis of non-small cell lung cancer.Frontiers in oncology · 2024Article
- Significance of preoperative blood tests in the prognosis of colorectal cancer: A prospective, multicenter study from Hungary.Journal of clinical laboratory analysis · 2022Article
- Markers of Prognosis for Early Stage Cervical Cancer Patients (Stage IB1, IB2) Undergoing Surgical Treatment.Frontiers in oncology · 2021Article
- Correlation analysis and clinical significance of CA125, HE4, DDI, and FDP in type II epithelial ovarian cancer.Medicine · 2020Observational
- Neutrophil extracellular traps enhance procoagulant activity in patients with oral squamous cell carcinoma.Journal of cancer research and clinical oncology · 2019Article
- Values of thoracic contrast-enhanced computed tomography in detecting incidental pulmonary thromboembolism in patients with malignant tumors.Oncology letters · 2019Article
- Lung Cancer Complicated With Asymptomatic Pulmonary Embolism: Clinical Analysis of 84 Patients.Technology in cancer research & treatment · 2017Article
- The comparison of plasma D-dimer levels in benign and malignant tumors of cervix, ovary and uterus.International journal of hematology-oncology and stem cell research · 2015Article
- [Clinical features in 23 lung cancer patients complicated with pulmonary thromboembolism].Zhongguo fei ai za zhi = Chinese journal of lung cancer · 2014Article
- Clinical significance of coagulation assays in metastatic pancreatic adenocarcinoma.Journal of gastrointestinal cancer · 2013Article
- Prognostic Significance of DR-70 Levels in Dysplastic Colorectal Polyps.Gastroenterology research and practice · 2013Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Malignant tumors are often accompanied by increased risk for procoagulant activity, thrombosis and embolism. As a marker indicating such disturbancies is D-dimer, a product of fibrinolysis. In this retrospective study almost 300 patients with malignant tumors were evaluated. During LMWH treatment (as thromboprophylaxis) the highest frequency of VTE with worst prognosis occurred in pancreatic cancer (partly due to the late discovery) followed by ovarian, colonic and breast cancers. Also, increased D-dimer level correlated with progression (stages) and high mortality rate. Furthermore, D-dimer showed very similar or better prognostic activity than the clinically widely used classic tumor markers and suggested to use it as an additional value..
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.