Evidence map›Paper›PMID 22286571›Full record

ArticleInternational archives of allergy and immunology2012

The impact of cigarette smoking on asthma: a population-based international cohort study.

Isa Cerveri, Lucia Cazzoletti, Angelo G Corsico, Alessandro Marcon, Rosanna Niniano, Amelia Grosso, Vanessa Ronzoni, Simone Accordini, Christer Janson, Isabelle Pin and 2 more

Registry-linked trialOpen access · bronzeAbstract readMulticenter Study
In one paragraph

Article in International archives of allergy and immunology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03207620 (Interrelation Between Bronchial Asthma and Smoking), which is not on this map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
3.5field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03207620 completednot on this mapstarted 2018, after this paper: background citation

Interrelation Between Bronchial Asthma and Smoking

TypeobservationalSponsorAssiut UniversityRan2018 to 2021Enrolled117ConditionsBronchial AsthmaArmsusing serum periostin and eotaxin-2 level, airway corticosteroid sensitivity
3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Asthma and Tobacco Smoking.Journal of personalized medicine · 2022
    Review
  15. Article
  16. Association of quality of life and disease control with cigarette smoking in patients with severe asthma.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2022
    Article
  17. Asthma and COVID-19: a dangerous liaison?Asthma research and practice · 2021
    Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Isa CerveriDivision of Respiratory Diseases, IRCCS San Matteo Hospital Foundation, University of Pavia, Pavia, Italy.
Lucia Cazzoletti
Angelo G Corsico
Alessandro Marcon
Rosanna Niniano
Amelia Grosso
Vanessa Ronzoni
Simone Accordini
Christer Janson
Isabelle Pin
Valerie Siroux
Roberto de Marco
University of Pavia · ITUniversity of Verona · ITDepartment of Medical Sciences · RUInserm · FRUniversité Joseph Fourier · FR

Funding

COMMUNITY BASED STUDY ON OCCUPATIONAL ASTHMA, ECRHS-OAR01HL062633 · NHLBI · MUNICIPAL INSTITUTE OF MEDICAL RESEARCH · PI KOGEVINAS, MANOLIS · 1999 to 2001
$180k
NHLBI NIH HHS R01 HL62633-01
6 · The paper itself

Abstract

backgroundThe prevalence rates of smoking in subjects with asthma have frequently been reported as similar to those in the general population; however, available data are not up-to-date. There is only limited and somewhat conflicting information on the long-term effects of smoking on health outcomes among population-based cohorts of subjects with asthma. We aimed to investigate changes in smoking habits and their effects on forced expiratory volume in 1 s (FEV(1)) in subjects with asthma in comparison with the rest of the population, focusing on the healthy smoker effect.

methodsWe studied 9,092 subjects without asthma and 1,045 with asthma at baseline who participated in both the European Community Respiratory Health Survey I (20-44 years old in 1991-1993) and II (1999-2002).

resultsAt follow-up, smoking was significantly less frequent among subjects with asthma than in the rest of the population (26 vs. 31%; p < 0.001). Subjects with asthma who were already ex-smokers at the beginning of the follow-up in the 1990 s had the highest mean asthma score (number of reported asthma-like symptoms, range 0-5), probably as a result of the healthy smoker effect (2.80 vs. 2.44 in never smokers, 2.19 in quitters and 2.24 in smokers; p < 0.001). The influence of smoking on FEV(1) decline did not depend on asthma status. Smokers had the highest proportion of subjects with chronic cough/phlegm (p < 0.01).

conclusionOne out of 4 subjects with asthma continues smoking and reports significantly more chronic cough and phlegm than never smokers and ex-smokers. This stresses the importance of smoking cessation in all patients with asthma, even in those with less severe asthma.

Indexed as

AdultAsthmaBronchial Provocation TestsCohort StudiesCoughFemaleForced Expiratory VolumeHumansLongitudinal StudiesMaleSmokingYoung Adult

Identifiers

PMID22286571
PMCPMC3696371
OpenAlexW2034410648

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.