ArticleJournal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy2012
A case of novel swine influenza A (H1N1) pneumonia complicated with virus-associated hemophagocytic syndrome.
Article in Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Influenza as a Less Commonly Recognized Cause of Hemophagocytic Lymphohistiocytosis: A Systematic Review of Case Reports and Case Series.European journal of haematology · 2026Pooled it
- The intersection of influenza infection and autoimmunity.Frontiers in immunology · 2025Review
- Diagnostic difficulties of AH1N1 influenza infection in children with acute lymphoblastic leukemia: Two case reports.Medicine · 2020Article
- Impact of severe hematological abnormalities in the outcome of hospitalized patients with influenza virus infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Observational
- H1N1 Infection-Related Hemophagocytic Lymphohistiocytosis in a Child.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2013Article
- Discrepancy of in-vitro data and clinical efficacy of micafungin against Candida tropicalis endophthalmitis.Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy · 2012Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Influenza related to complications such as pneumonia and encephalitis have sporadically been reported. However, influenza A (H1N1)-virus-associated hemophagocytic syndrome (VAHS) has rarely been reported. A 39-year old woman complained of high fever and was referred to us. Chest infiltrations in both lungs and a positive polymerase chain reaction (PCR) for novel swine origin influenza A (H1N1) in bronchial alveolar lavage fluid (BALF) specimen was confirmed and she was diagnosed with influenza A (H1N1) pneumonia. Pancytopenia was found, and hemophagocytic syndrome (HPS) was diagnosed by bone marrow aspiration. Following intravenous administration of antiflu drug and combination therapy of steroid pulse and erythromycin IV, the patient’s respiratory dysfunction and lab data gradually improved and she was discharged on day 21. Whereas secondary HPS related to viral infections such as Epstein–Barr virus, cytomegalovirus, and human herpesvirus type 6 are commonly seen, H1N1 pneumonia complicated with secondary VAHS is rare.
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