Evidence map›Paper›PMID 22285877›Full record

ArticleMagnetic resonance imaging2012

Cross-sectional investigation of correlation between hepatic steatosis and IVIM perfusion on MR imaging.

James T Lee, Joy Liau, Paul Murphy, Michael E Schroeder, Claude B Sirlin, Mark Bydder

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  12. [Progress of diffusion weighted imaging based on monoexponential and biexponential models as a clinical application for hepatic disease].Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology · 2015
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

James T LeeDepartment of Radiology, Division of Emergency and Abdominal Radiology, University of Kentucky, Lexington, KY 40536-0293, USA.
Joy Liau
Paul Murphy
Michael E Schroeder
Claude B Sirlin
Mark Bydder

Funding

MR Imaging of Non-Alcoholic Fatty Liver DiseaseR01DK075128 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SIRLIN, CLAUDE B · 2006 to 2010
$2.4M
NIDDK NIH HHS R01 DK075128
6 · The paper itself

Abstract

The purpose of this study was to investigate the relationship between liver fat fraction (FF) and diffusion parameters derived from the intravoxel incoherent motion (IVIM) model. Thirty-six subjects with suspected nonalcoholic fatty liver disease underwent diffusion-weighted magnetic resonance imaging with 10 b-values and spoiled gradient recalled echo imaging with six echoes for fat quantification. Correlations were measured between FF, transverse relaxivity (R2), diffusivity (D) and perfusion fraction (f). The primary finding was that no significant correlation was obtained for D vs. FF or f vs. FF. Significant correlations were obtained for D vs. R2 (r=-0.490, P=.002) and f vs. D (r=-0.458, P=.005). The conclusion is that hepatic steatosis does not affect measurement of perfusion or diffusion and therefore is unlikely to confound the use of apparent diffusivity to evaluate hepatic fibrosis.

Indexed as

AdolescentAdultChildCross-Sectional StudiesDiffusion Magnetic Resonance ImagingFatty LiverFemaleHumansMaleMiddle AgedNon-alcoholic Fatty Liver DiseaseProspective StudiesSensitivity and Specificity

Identifiers

PMID22285877
PMCPMC3327769

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.