Evidence map›Paper›PMID 22284666›Full record

ReviewPlacenta2012

Rat placentation: an experimental model for investigating the hemochorial maternal-fetal interface.

M J Soares, D Chakraborty, M A Karim Rumi, T Konno, S J Renaud

Abstract readReview
In one paragraph

Review in Placenta, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 122 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
122citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

122 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guidelines for assessing maternal cardiovascular physiology during pregnancy and postpartum.American journal of physiology. Heart and circulatory physiology · 2024
    Guideline
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62 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

M J SoaresInstitute for Reproductive Health and Regenerative Medicine, Department of Pathology & Laboratory Medicine, University of Kansas Medical Center, 3901 Rainbow Blvd, Kansas City, KS 66160, USA. msoares@kumc.edu
D Chakraborty
M A Karim Rumi
T Konno
S J Renaud

Funding

TROPHOBLAST DIFFERENTIATIONR01HD020676 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI MICHAEL J SOARES · 1986 to 2026
$10.1M
Decidual Cell Adaptations to Physiological StressorsR01HD055523 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2007 to 2011
$1.5M
Dissecting Uterine Progesterone ResistanceR21HD066406 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2012 to 2013
$404k
Genetics of DecidualizationR21HD060115 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2010 to 2011
$404k
Physiological Genomics of PregnancyR21HD049503 · NICHD · UNIVERSITY OF KANSAS MEDICAL CENTER · PI SOARES, MICHAEL J · 2006 to 2007
$330k
CIHRNICHD NIH HHS HD049503NICHD NIH HHS HD055523NICHD NIH HHS HD060115NICHD NIH HHS HD20676NICHD NIH HHS R01 HD020676NICHD NIH HHS R01 HD055523NICHD NIH HHS R21 HD049503NICHD NIH HHS R21 HD060115NICHD NIH HHS R21 HD066406
6 · The paper itself

Abstract

The rat possesses hemochorial placentation with deep intrauterine trophoblast cell invasion and trophoblast-directed uterine spiral artery remodeling; features shared with human placentation. Recognition of these similarities spurred the establishment of in vitro and in vivo research methods using the rat as an animal model to address mechanistic questions regarding development of the hemochorial placenta. The purpose of this review is to provide the requisite background to help move the rat to the forefront in placentation research.

Indexed as

Maternal-Fetal ExchangePlacentationAnimalsFemaleHumansKiller Cells, NaturalPlacentaPregnancyRatsSpecies SpecificityUterine ArteryUterus

Identifiers

PMID22284666
PMCPMC3288880

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.