Evidence map›Paper›PMID 22283476›Full record

ArticleJournal of women's health (2002)2012

Reproductive history and hot flashes in perimenopausal women.

Karen Nakano, Ellen Pinnow, Jodi A Flaws, John D Sorkin, Lisa Gallicchio

Abstract read
In one paragraph

Article in Journal of women's health (2002), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
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  3. Age at menarche and risk of vasomotor menopausal symptoms: a pooled analysis of six studies.BJOG : an international journal of obstetrics and gynaecology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Karen NakanoDepartment of Epidemiology and Preventive Medicine, University of Maryland School of Medicine, Baltimore, Maryland, USA.
Ellen Pinnow
Jodi A Flaws
John D Sorkin
Lisa Gallicchio
University of Maryland, Baltimore · USBaltimore VA Medical Center · USUniversity of Illinois Urbana-Champaign · USWeinberg Medical Physics (United States) · US

Funding

University of Maryland Claude D. Pepper Older Americans Independence Center (UM-OAIC)P30AG028747 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI ALICE S. RYAN · 2006 to 2026
$28.9M
Risk Factors for Hot Flashes in Mid-Life WomenR01AG018400 · NIA · UNIVERSITY OF MARYLAND BALTIMORE · PI FLAWS, JODI A. · 2001 to 2011
$4.1M
Clinical Research Curriculum AwardK30RR022682 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI ROGHMANN, MARY-CLAIRE · 2005 to 2011
$2.1M
NCRR NIH HHS 5K30RR022682NIA NIH HHS 5P30AG028747NIA NIH HHS AG018400NIA NIH HHS P30 AG028747
6 · The paper itself

Abstract

backgroundHot flashes affect up to 75% of women undergoing the menopausal transition. They are among the most common health problems for perimenopausal women and are associated with a decrease in quality of life. The goal of this study was to examine the associations between reproductive history variables and midlife hot flashes.

methodsData were analyzed from 388 perimenopausal women who participated in the Midlife Health Study, a population-based, cross-sectional study of 639 women aged 45-54 years living in the Baltimore metropolitan region.

resultsThe unadjusted analyses showed that none of the reproductive history variables analyzed, including age at menarche, number of live births, ever having been pregnant, age at first birth, age at last pregnancy, and history of oral contraceptive use, were associated with ever experiencing hot flashes. However, after adjusting for race, age group, marital status, education, employment, total family income, smoking and alcohol status, and body mass index (BMI), age at last pregnancy was significantly associated with moderate to severe hot flashes. Specifically, participants who were ≥36 years of age at last pregnancy were less likely to report moderate or severe hot flashes than those ≤35 years of age at last pregnancy (odds ratio 0.36, 95% confidence interval 0.16, 0.84).

conclusionsIn this study, in general, characteristics of reproductive history were not associated with midlife hot flashes. However, there are a number of potentially modifiable factors that are associated with the occurrence of hot flashes. Thus, alternatives may be available when hormone treatment is contraindicated.

Indexed as

PerimenopauseReproductive HealthCross-Sectional StudiesExerciseFemaleHealth SurveysHumansLogistic ModelsPostmenopausePregnancyRisk FactorsSocioeconomic Factors

Identifiers

PMID22283476
PMCPMC3321671
OpenAlexW1981966287

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.