Trial reportSchizophrenia bulletin2013
A randomized controlled trial of family intervention for co-occurring substance use and severe psychiatric disorders.
Trial report in Schizophrenia bulletin, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 5 syntheses or guidelines pooled it, 64 citations in OpenAlex.
- Family-based interventions versus standard care for people with schizophrenia.The Cochrane database of systematic reviews · 2024Pooled it
- Psychosocial Interventions to Improve Psychological, Social and Physical Wellbeing in Family Members Affected by an Adult Relative's Substance Use: A Systematic Search and Review of the Evidence.International journal of environmental research and public health · 2021Pooled it
- Psychosocial interventions for people with both severe mental illness and substance misuse.The Cochrane database of systematic reviews · 2019Pooled it
- Translating evidence to patient care through caregivers: a systematic review of caregiver-mediated interventions.BMC medicine · 2018Pooled it
- Psychoeducation for schizophrenia.The Cochrane database of systematic reviews · 2011Pooled it
- Trans-Sector Integrated Treatment in Psychosis and Addiction.Deutsches Arzteblatt international · 2015Trial
- Cognitive Enhancement Therapy in substance misusing schizophrenia: results of an 18-month feasibility trial.Schizophrenia research · 2015Trial
- Managing psychiatric comorbidity within versus outside of methadone treatment settings: a randomized and controlled evaluation.Addiction (Abingdon, England) · 2013Trial
- Family-centered interventions for people with substance use disorders in low-and middle-income country settings: a scoping review.The International journal on drug policy · 2026Article
- Guidelines for the nursing care of patients diagnosed with dual diagnosis in psychiatric hospitals of Ghana: a qualitative study.BMC nursing · 2026Article
- Bipolar disorder.Lancet (London, England) · 2025Review
- Psychosocial Management of First-Episode Psychosis and Schizophrenia: Synopsis of the US Department of Veterans Affairs and US Department of Defense Clinical Practice Guidelines.Schizophrenia bulletin · 2025Article
- Pilot development and feasibility of telehealth Community Reinforcement and Family Training (CRAFT) for early psychosis and substance use.Psychiatry research · 2022Article
- Substance Use in Relation to Mental Illness: A Study of Mexican-Origin Latinos with Schizophrenia and Their Family Members.Health & social work · 2022Article
- Cariprazine to Treat Schizophrenia and Bipolar Disorder in Adults.Psychopharmacology bulletin · 2020Review
- Caregiving for Relatives with Psychiatric Disorders vs. Co-Occurring Psychiatric and Substance Use Disorders.The Psychiatric quarterly · 2018Article
- Assessment of clinical co-morbidities.Indian journal of psychiatry · 2018Review
- Psychosocial Interventions in Reducing Cannabis Use in Early Phase Psychosis: A Canadian Survey of Treatments Offered.Canadian journal of psychiatry. Revue canadienne de psychiatrie · 2016Article
- Family interventions in Schizophrenia: promise and pitfalls over 30 years.Current psychiatry reports · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 8 institutions in 1 country.
Funding
Abstract
Substance use disorders have a profound impact on the course of severe mental illnesses and on the family, but little research has evaluated the impact of family intervention for this population. To address this question, a randomized controlled trial was conducted comparing a brief (2-3 mo) Family Education (ED) program with a longer-term (9-18 mo) program that combined education with teaching communication and problem-solving skills, Family Intervention for Dual Disorders (FIDD). A total of 108 clients (77% schizophrenia-spectrum) and a key relative were randomized to either ED or FIDD and assessed at baseline and every 6 months for 3 years. Rates of retention of families in both programs were moderate. Intent-to-treat analyses indicated that clients in both programs improved in psychiatric, substance abuse, and functional outcomes, as did key relatives in knowledge of co-occurring disorders, burden, and mental health functioning. Clients in FIDD had significantly less severe overall psychiatric symptoms and psychotic symptoms and tended to improve more in functioning. Relatives in FIDD improved more in mental health functioning and knowledge of co-occurring disorders. There were no consistent differences between the programs in substance abuse severity or family burden. The findings support the utility of family intervention for co-occurring disorders, and the added benefits of communication and problem-solving training, but also suggest the need to modify these programs to retain more families in treatment in order to provide them with the information and skills they need to overcome the effects of these disorders.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.