ReviewJournal of cardiovascular translational research2012
Mathematical modeling and simulation of ventricular activation sequences: implications for cardiac resynchronization therapy.
Review in Journal of cardiovascular translational research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
9 citing papers in PubMed.
- Reconstructing ventricular activation sequences from epicardial data: Insights from Geodesic Back-Propagation optimization in porcine models.Computers in biology and medicine · 2025Article
- Adaptive heartbeat regulation using double deep reinforcement learning in a Markov decision process framework.Scientific reports · 2025Article
- A computational model of rabbit geometry and ECG: Optimizing ventricular activation sequence and APD distribution.PloS one · 2022Article
- Implantable Cardioverter-Defibrillators With Versus Without Resynchronization Therapy in Patients With a QRS Duration >180 ms.Journal of the American College of Cardiology · 2017Article
- Article
- Imaging of Ventricular Fibrillation and Defibrillation: The Virtual Electrode Hypothesis.Advances in experimental medicine and biology · 2015Review
- Patient-specific modelling of cardiac electrophysiology in heart-failure patients.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2014Article
- Fibroblast-myocyte electrotonic coupling: does it occur in native cardiac tissue?Journal of molecular and cellular cardiology · 2014Review
- Modeling cardiac electromechanics and mechanoelectrical coupling in dyssynchronous and failing hearts: insight from adaptive computer models.Journal of cardiovascular translational research · 2012Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Next to clinical and experimental research, mathematical modeling plays a crucial role in medicine. Biomedical research takes place on many different levels, from molecules to the whole organism. Due to the complexity of biological systems, the interactions between components are often difficult or impossible to understand without the help of mathematical models. Mathematical models of cardiac electrophysiology have made a tremendous progress since the first numerical ECG simulations in the 1960s. This paper briefly reviews the development of this field and discusses some example cases where models have helped us forward, emphasizing applications that are relevant for the study of heart failure and cardiac resynchronization therapy.
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Registered trials
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