Evidence map›Paper›PMID 22281832›Full record

ReviewAmerican journal of respiratory and critical care medicine2012

Anemia in critical illness: insights into etiology, consequences, and management.

Shailaja J Hayden, Tyler J Albert, Timothy R Watkins, Erik R Swenson

3 registry-linked trialsAbstract readReview
In one paragraph

Review in American journal of respiratory and critical care medicine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 98 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
98citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05382065 completednot on this mapstarted 2022, after this paper: background citation

The Correlation Between Period of Anemia and Duration of Mechanical Ventilation in Patients Admitted to the Surgical Intensive Care Unit

TypeobservationalSponsorMahidol UniversityRan2022 to 2024Enrolled236ConditionsAnemia, Mechanical Ventilation, Critically Ill, Intensive Care Unit
NCT06542393 phase2recruitingnot on this mapstarted 2024, after this paper: background citation

Patient Blood Manegement (PBM) as Perioperative Strategy to Anemic Patients Who Will be Submitted to Coronary Artery Bypass Graft (CABG).

TypeinterventionalSponsorFederal University of São PauloRan2024 to 2026Enrolled120ConditionsAnemia, Coronary Disease, Coronary Artery Disease, Coronary StenosisArmsErythropoietin, blood transfusion
NCT06560164 narecruitingnot on this mapstarted 2024, after this paper: background citation

Restrictive Versus Liberal Thresholds for Red Blood Cell Transfusion in ExtraCorporeal Membrane Oxygenation - the TREC Study

TypeinterventionalSponsorAcademisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)Ran2024 to 2028Enrolled526ConditionsTransfusion, Red Blood Cell, Extracorporeal Membrane Oxygenation, AnemiaArmsRed Blood Cell transfusion
3 · Its place in the literature

Who cites it

98 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. High-Dose Vitamin DJPEN. Journal of parenteral and enteral nutrition · 2018
    Trial
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Observational
  9. Observational
  10. Observational
  11. Article
  12. Article
  13. Article
  14. Review
  15. Comparative analysis of outcomes between anemic and non-anemic critically ill elderly patients in a geriatric ICU in Egypt: A focused study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  16. Article
  17. Article
  18. Article
  19. Anemia of Inflammation.Advances in experimental medicine and biology · 2025
    Review
  20. Article

38 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shailaja J HaydenDivision of Pulmonary and Critical Care Medicine, University of Washington, Seattle, Washington, USA.
Tyler J Albert
Timothy R Watkins
Erik R Swenson

Funding

Trauma and Acute Lung Injury: The Role of Red Blood Cell Storage and TransfusionK23GM086729 · NIGMS · UNIVERSITY OF WASHINGTON · PI WATKINS, TIMOTHY RYAN · 2009 to 2013
$718k
NIGMS NIH HHS K23 GM086729NIGMS NIH HHS K23GM086729
6 · The paper itself

Abstract

Anemia is common in the intensive care unit, and may be associated with adverse consequences. However, current options for correcting anemia are not without problems and presently lack convincing efficacy for improving survival in critically ill patients. In this article we review normal red blood cell physiology; etiologies of anemia in the intensive care unit; its association with adverse outcomes; and the risks, benefits, and efficacy of various management strategies, including blood transfusion, erythropoietin, blood substitutes, iron therapy, and minimization of diagnostic phlebotomy.

Indexed as

AnemiaCritical IllnessCritical CareErythrocytesErythrocyte TransfusionErythropoietinHematinicsHumansIntensive Care UnitsIronTrace ElementsErythropoietinHematinicsIronTrace Elements

Identifiers

PMID22281832
PMCPMC5448578

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.