ReviewThe Lancet. Infectious diseases2012
Surgical treatment of drug-resistant tuberculosis.
Review in The Lancet. Infectious diseases, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.
- Risk factors for pneumonia after radical gastrectomy for gastric cancer: a systematic review and meta-analysis.BMC cancer · 2025Pooled it
- The effect of surgery on the outcome of treatment for multidrug-resistant tuberculosis: a systematic review and meta-analysis.BMC infectious diseases · 2016Pooled it
- Cavitary penetration of levofloxacin among patients with multidrug-resistant tuberculosis.Antimicrobial agents and chemotherapy · 2015Trial
- Pulmonary tuberculosis and the surgeon.Lung India : official organ of Indian Chest Society · 2026Article
- Closure of TB pulmonary cavern using endobronchial valve placement.Oxford medical case reports · 2024Article
- Long term management of people with post-tuberculosis lung disease.The Korean journal of internal medicine · 2024Review
- Outcomes of patients undergoing lung resection for drug-resistant TB and the prognostic significance of pre-operative positron emission tomography/computed tomography (PET/CT) in predicting treatment failure.EClinicalMedicine · 2023Article
- Treated Dentin Matrix in Tissue Regeneration: Recent Advances.Pharmaceutics · 2022Review
- Review
- Adjunctive surgery versus medical treatment among patients with cavitary multidrug-resistant tuberculosis.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2021Article
- The development and validation of a diagnostic scoring system to differentiate pulmonary tuberculosis from non-tuberculosis pulmonary infections in HIV-infected patients with severe immune suppression.BMC infectious diseases · 2021Article
- Genomic analyses of Mycobacterium tuberculosis from human lung resections reveal a high frequency of polyclonal infections.Nature communications · 2021Observational
- A Case of Nasopharyngeal Mycobacteriosis with Bony Erosion of the External Skull Base.Case reports in otolaryngology · 2021Article
- Impact of adjuvant therapeutic surgery on the health-related quality of life of pulmonary tuberculosis patients.ERJ open research · 2020Article
- Cavitary tuberculosis: the gateway of disease transmission.The Lancet. Infectious diseases · 2020Review
- Closure of pulmonary cavity of a multidrug-resistant tuberculosis patient with catheter insertion - A case report.Journal of clinical tuberculosis and other mycobacterial diseases · 2020Article
- Pulmonary function and respiratory health after successful treatment of drug-resistant tuberculosis.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2019Article
- Treatment as prevention and other interventions to reduce transmission of multidrug-resistant tuberculosis.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2019Article
- Revisiting the evolution of tuberculosis therapy: historical reflections in the modern era.Oxford medical case reports · 2018Article
- Current Indications and Outcome of Pulmonary Resections for Tuberculosis Complications in Ibadan, Nigeria.Medical principles and practice : international journal of the Kuwait University, Health Science Centre · 2018Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
Abstract
The global emergence and spread of multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis has led to the re-examination of surgery as a possible adjunctive treatment. We present the case of a 26-year-old HIV-seronegative patient with XDR pulmonary tuberculosis refractory to medical therapy. Surgical resection of the patient's solitary cavitary lesion was done as adjunctive treatment, and a successful outcome with a combination of surgery and drug therapy was achieved. We review the history of surgical therapy for tuberculosis and reports of its role in treatment of MDR and XDR tuberculosis. 26 case series and cohort studies were included, and together showed that surgical resection is beneficial in the treatment of drug-resistant tuberculosis. However, the results might not be applicable in all settings because investigations were observational and typically included patients with less severe disease, and all surgeries were done at specialised thoracic-surgery centres. Well designed studies are needed to establish the efficacy of surgery in treatment of drug-resistant tuberculosis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.