ReviewCytokine2012
The role of cytokines and pathogen recognition molecules in fungal keratitis - Insights from human disease and animal models.
Review in Cytokine, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed, 1 synthesis or guideline pooled it, 72 citations in OpenAlex.
- Toll-like receptors in corneal ectasia: linking innate immunity to keratoconus.Molecular biology reports · 2026Pooled it
- Inhibition of TREM-1 and Dectin-1 Alleviates the Severity of Fungal Keratitis by Modulating Innate Immune Responses.PloS one · 2016Trial
- Advances in the molecular pathogenesis ofFrontiers in cellular and infection microbiology · 2026Review
- Fungal Keratitis in Northwestern Spain: Epidemiology, Risk Factors and Outcomes.Journal of fungi (Basel, Switzerland) · 2024Article
- Aspergillus fumigatus Hypoxia Adaptation Is Critical for the Establishment of Fungal Keratitis.Investigative ophthalmology & visual science · 2024Article
- Three cases of recalcitrant Paecilomyces keratitis in Southern California within a short period.Journal of ophthalmic inflammation and infection · 2024Article
- Living with your biome: how the bacterial microbiome impacts ocular surface health and disease.Expert review of ophthalmology · 2024Article
- The Aspergillus fumigatus UPR is variably activated across nutrient and host environments and is critical for the establishment of corneal infection.PLoS pathogens · 2023Article
- A New Proposed Symbiotic Plant-Herbivore Relationship betweenMicroorganisms · 2023Article
- Challenges in the diagnosis and management of atypical fungal keratitis during the COVID-19 pandemic: a case series.Access microbiology · 2023Article
- Pseudomonas Synergizes with Fluconazole againstInfection and immunity · 2022Article
- Pathogenic Aspergillus and Fusarium as important causes of blinding corneal infections - the role of neutrophils in fungal killing, tissue damage and cytokine production.Current opinion in microbiology · 2021Review
- A novel 3D culture model of fungal keratitis to explore host-pathogen interactions within the stromal environment.Experimental eye research · 2021Article
- Indoleamine 2,3-Dioxygenase Regulates Macrophage Recruitment, Polarization and Phagocytosis in Aspergillus Fumigatus Keratitis.Investigative ophthalmology & visual science · 2020Article
- Human fusariosis: An emerging infection that is difficult to treat.Revista da Sociedade Brasileira de Medicina Tropical · 2020Review
- CRISPR/Cas9-Mediated Gene Replacement in the Fungal Keratitis PathogenMicroorganisms · 2019Article
- Aspergillus fumigatus corneal infection is regulated by chitin synthases and by neutrophil-derived acidic mammalian chitinase.European journal of immunology · 2019Article
- Inhibition of LOX-1 alleviates the proinflammatory effects of high-mobility group box 1 inInternational journal of ophthalmology · 2019Article
- The Expression of Dectin-1, Irak1 and Rip2 During the Host Response to Aspergillus fumigatus.Mycopathologia · 2018Article
- Microplasma Jet Arrays as a Therapeutic Choice for Fungal Keratitis.Scientific reports · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Fungal infections of the cornea are an important cause of blindness and visual impairment worldwide, with contact lens wear being the main risk factor in the USA and other industrialized countries, and traumatic injury being the main risk factor in developing countries. In this review, we highlight recent advances in the understanding of the host response to Aspergillus and Fusarium species in infected human corneal tissue and in mouse models of fungal keratitis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.