ArticleCellular logistics2011
ThANKs for the repeat: Intracellular pathogens exploit a common eukaryotic domain.
Article in Cellular logistics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 30 citations in OpenAlex.
- Complete telomere-to-telomere genomes uncover virulence evolution conferred by chromosome fusion in oomycete plant pathogens.Nature communications · 2024Article
- The life cycle-dependent transcriptional profile of the obligate intracellular amoeba symbiont Amoebophilus asiaticus.FEMS microbiology ecology · 2022Article
- The draft genome of strainPeerJ · 2019Article
- An Update on Host-Pathogen Interplay and Modulation of Immune Responses during Orientia tsutsugamushi Infection.Clinical microbiology reviews · 2018Review
- Orientia tsutsugamushi Modulates Endoplasmic Reticulum-Associated Degradation To Benefit Its Growth.Infection and immunity · 2018Article
- Molecular architecture of an N-formyltransferase from Salmonella enterica O60.Journal of structural biology · 2017Article
- The Enterococcus faecalis virulence factor ElrA interacts with the human Four-and-a-Half LIM Domains Protein 2.Scientific reports · 2017Article
- Orientia tsutsugamushi Ank9 is a multifunctional effector that utilizes a novel GRIP-like Golgi localization domain for Golgi-to-endoplasmic reticulum trafficking and interacts with host COPB2.Cellular microbiology · 2017Article
- Enzymes required for the biosynthesis of N-formylated sugars.Current opinion in structural biology · 2016Review
- Virulence genes of Rickettsia rickettsii are differentially modulated by either temperature upshift or blood-feeding in tick midgut and salivary glands.Parasites & vectors · 2016Article
- Nothing in Evolution Makes Sense Except in the Light of Genomics: Read-Write Genome Evolution as an Active Biological Process.Biology · 2016Review
- Mechanism and Function of Type IV Secretion During Infection of the Human Host.Microbiology spectrum · 2016Review
- Protein Repeats from First Principles.Scientific reports · 2016Article
- Orientia tsutsugamushi Strain Ikeda Ankyrin Repeat-Containing Proteins Recruit SCF1 Ubiquitin Ligase Machinery via Poxvirus-Like F-Box Motifs.Journal of bacteriology · 2015Article
- Babela massiliensis, a representative of a widespread bacterial phylum with unusual adaptations to parasitism in amoebae.Biology direct · 2015Article
- New role for the ankyrin repeat revealed by a study of the N-formyltransferase from Providencia alcalifaciens.Biochemistry · 2015Article
- Secretome of obligate intracellular Rickettsia.FEMS microbiology reviews · 2015Review
- Orientia tsutsugamushi ankyrin repeat-containing protein family members are Type 1 secretion system substrates that traffic to the host cell endoplasmic reticulum.Frontiers in cellular and infection microbiology · 2014Article
- Structure of the Legionella effector AnkX reveals the mechanism of phosphocholine transfer by the FIC domain.The EMBO journal · 2013Article
- Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Bacterial pathogens are renowned cell biologists that subvert detrimental host responses by manipulating eukaryotic protein function. A select group of pathogens use a specialized type IV secretion system (T4SS) as a conduit to deliver an arsenal of proteins into the host cytosol where they interact with host proteins. The translocated "effectors" have garnered increased attention because they uncover novel aspects of host-pathogen interactions at the subcellular level. This review presents a group of effectors termed Anks that possess eukaryotic-like ankyrin repeat domains that mediate proteinprotein interactions and are critical for effector function. Interestingly, most known prokaryotic Anks are produced by bacteria that devote much of their time to replicating inside eukaryotic cells. Ank proteins represent a fascinating and versatile family of effectors exploited by bacterial pathogens and are proving useful as tools to study eukaryotic cell biology.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.