ArticleJournal of research in medical sciences : the official journal of Isfahan University of Medical Sciences2011
Comparative study of serum MDA and vitamin C levels in non-smokers, chronic smokers and chronic smokers with acute myocardial infarction in men.
Article in Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 22 citations in OpenAlex.
- Impact of smokeless tobacco on psychological and oxidative stress in unemployed indian youth.Amino acids · 2024Article
- Influence of rs1746048 SNPs on clinical manifestations and incidence of acute myocardial infarction in Guangxi Han population.International journal of clinical and experimental pathology · 2019Article
- More to gain: dietary energy density is related to smoking status in US adults.BMC public health · 2018Article
- Correlation of rs1122608 SNP with acute myocardial infarction susceptibility and clinical characteristics in a Chinese Han population: A case-control study.Anatolian journal of cardiology · 2018Article
- Erythrocyte Antioxidant Defenses Against Cigarette Smoking in Ischemic Heart Disease.Journal of clinical and diagnostic research : JCDR · 2015Article
- Effect of smoking on serum xanthine oxidase, malondialdehyde, ascorbic acid and α-tocopherol levels in healthy male subjects.Pakistan journal of medical sciencesArticle
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
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Abstract
backgroundIt is a well-known fact that there is increased oxidative stress and decreased serum antioxidant levels in smokers than in non-smokers. In this study, the aim was to compare the serum levels of malondialdehyde (MDA), a lipid peroxidation product and vitamin C, an antioxidant, between non- smokers (Group A) and chronic smokers (Group B) and also between chronic smokers (Group B) and chronic smokers with acute myocardial infarction (AMI) (Group C).
methodsThirty six non-smokers and 36 chronic smokers appropriately matched with AMI patients were selected. Thirty six smokers with AMI were selected from Hanagal Kumareshwara hospital, Bagalkot, Karnataka, India. Fasting blood sample was collected in group A and group B. In AMI patients, blood sample was collected before any intervention. Serum levels of MDA and vitamin C were estimated. Statistical analysis was done by t test using SPSS version 11. The p< 0.05 was considered statistically significant. All the results were expressed as mean ± SD.
resultsThe MDA and vitamin C were compared between Group A and Group B and also between Group B and Group C. There was a significant rise in MDA (p<0.0001) and significant decrease in vitamin C (p<0.01) in Group B compared to Group A. There was a significant rise in MDA (p<0.0001) and significant decrease in vitamin C (p<0.001) in Group C compared to Group B.
conclusionsThe increase in serum MDA level and decrease in vitamin C was found in chronic smokers compared to non-smokers. It was also found that there is increase in serum MDA and decrease in vitamin C in smokers with AMI compared with smokers without AMI, and the reason for this inter-subject variability of MDA and vitamin C levels may be due to gene-environmental factors.
Indexed as
Identifiers
22279473PMC3263094W2125067560What OpenQuestion holds
Registered trials
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