Evidence map›Paper›PMID 22279114›Full record

ArticleBMJ (Clinical research ed.)2012

Decline in mortality from coronary heart disease in Poland after socioeconomic transformation: modelling study.

Piotr Bandosz, Martin O'Flaherty, Wojciech Drygas, Marcin Rutkowski, Jacek Koziarek, Bogdan Wyrzykowski, Kathleen Bennett, Tomasz Zdrojewski, Simon Capewell

Open access · hybridAbstract read
In one paragraph

Article in BMJ (Clinical research ed.), 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
58citing papers in PubMed, 1 pooled it
21.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

58 citing papers in PubMed, 1 synthesis or guideline pooled it, 175 citations in OpenAlex.

  1. Pooled it
  2. Trial
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  5. A Modeling Study for Hip Fracture Rates in Romania.Journal of clinical medicine · 2025
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  15. Trends in premature mortality rates among the Polish population due to cardiovascular diseases.International journal of occupational medicine and environmental health · 2022
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Piotr BandoszDepartment of Hypertension and Diabetology, Medical University in Gdansk, Poland.
Martin O'Flaherty
Wojciech Drygas
Marcin Rutkowski
Jacek Koziarek
Bogdan Wyrzykowski
Kathleen Bennett
Tomasz Zdrojewski
Simon Capewell
Gdańsk Medical University · PLInstitute of Cardiology · PLSt. James's Hospital · IE

Funding

Medical Research Council 91367Medical Research Council G0900847
6 · The paper itself

Abstract

objectivesTo examine how much of the observed rapid decrease in mortality from coronary heart disease in Poland after the political, social, and economic transformation in the early 1990s could be explained by the use of medical and surgical treatments and how much by changes in cardiovascular risk factors.

designA modelling study.

settingSources of data included controlled trials and meta-analyses, national surveys, and official statistics.

participantsPopulation of adults aged 25-74 in Poland in 1991-2005.

main outcome measuresNumber of deaths prevented or postponed in 2005 attributable to specific treatments for coronary heart disease and changes in risk factors. A previously validated epidemiological model for coronary heart disease was used to combine and analyse data on the uptake and effectiveness of specific cardiac treatments and changes in risk factors. The observed fall in deaths from coronary heart disease from 1991 to 2005 was then partitioned among specific treatments and risk factor changes.

resultsFrom 1991 to 2005, the death rate from coronary heart disease in Poland halved, resulting in 26,200 fewer coronary deaths in 2005 in people aged 25-74. About 37% (minimum estimate 13%, maximum estimate 77%) of this decrease was attributable to treatments, including treatments for heart failure (12%), initial treatments for acute coronary syndrome (9%), secondary prevention treatments after myocardial infarction or revascularisation (7%), chronic angina treatments (3%), and other treatments (6%). About 54% of the fall was attributed to changes in risk factors (minimum estimate 41%, maximum estimate 65%), mainly reductions in total cholesterol concentration (39%) and an increase in leisuretime physical activity (10%); however, these were partially offset by increases in body mass index (-4%) and prevalence of diabetes (-2%). Blood pressure fell in women, explaining about 29% of their decrease in mortality, but rose in men generating a negative influence (-8%). About 15% of the observed decrease in mortality was attributable to reduced smoking in men but was negligible in women.

conclusionsOver half of the recent fall in mortality from coronary heart disease in Poland can be attributed to reductions in major risk factors and about one third to evidence based medical treatments.

Indexed as

Models, StatisticalAcute Coronary SyndromeAdultAgedAngina PectorisBlood PressureBody Mass IndexCholesterolCoronary DiseaseDelivery of Health CareDiabetes MellitusEpidemiologic StudiesFemaleHeart FailureHumansMaleCholesterol

Identifiers

PMID22279114
PMCPMC3266431
OpenAlexW2019822535

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.