ArticleNucleic acids research2012
The conserved 5' apical hairpin stem loops of bamboo mosaic virus and its satellite RNA contribute to replication competence.
Article in Nucleic acids research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed.
- Alphaflexiviridae in Focus: Genomic Signatures, Conserved Elements and Viral-Driven Cellular Remodeling.Viruses · 2025Review
- Trade-off between local replication and long-distance dissemination during experimental evolution of a satellite RNA.Frontiers in microbiology · 2023Article
- Molecular interactions of plant viral satellites.Virus genes · 2021Review
- A conserved RNA structure is essential for a satellite RNA-mediated inhibition of helper virus accumulation.Nucleic acids research · 2019Article
- An E3 ubiquitin ligase from Nicotiana benthamiana targets the replicase of Bamboo mosaic virus and restricts its replication.Molecular plant pathology · 2019Article
- Article
- Phylogeography and Coevolution of Bamboo Mosaic Virus and Its Associated Satellite RNA.Frontiers in microbiology · 2017Article
- Interfering Satellite RNAs ofFrontiers in microbiology · 2017Review
- Biologically-supported structural model for a viral satellite RNA.Nucleic acids research · 2015Article
- The molecular basis for flexibility in the flexible filamentous plant viruses.Nature structural & molecular biology · 2015Article
- Two key arginine residues in the coat protein of Bamboo mosaic virus differentially affect the accumulation of viral genomic and subgenomic RNAs.Molecular plant pathology · 2014Article
- Genetic diversity and evolution of satellite RNAs associated with the bamboo mosaic virus.PloS one · 2014Article
- Transgenic resistance to Bamboo mosaic virus by expression of interfering satellite RNA.Molecular plant pathology · 2013Article
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6 authors.
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Abstract
Satellite RNAs associated with Bamboo mosaic virus (satBaMVs) depend on BaMV for replication and encapsidation. Certain satBaMVs isolated from natural fields significantly interfere with BaMV replication. The 5' apical hairpin stem loop (AHSL) of satBaMV is the major determinant in interference with BaMV replication. In this study, by in vivo competition assay, we revealed that the sequence and structure of AHSL, along with specific nucleotides (C(60) and C(83)) required for interference with BaMV replication, are also involved in replication competition among satBaMV variants. Moreover, all of the 5' ends of natural BaMV isolates contain the similar AHSLs having conserved nucleotides (C(64) and C(86)) with those of interfering satBaMVs, suggesting their co-evolution. Mutational analyses revealed that C(86) was essential for BaMV replication, and that replacement of C(64) with U reduced replication efficiency. The non-interfering satBaMV interfered with BaMV replication with the BaMV-C64U mutant as helper. These findings suggest that two cytosines at the equivalent positions in the AHSLs of BaMV and satBaMV play a crucial role in replication competence. The downregulation level, which is dependent upon the molar ratio of interfering satBaMV to BaMV, implies that there is competition for limited replication machinery.
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