Evidence map›Paper›PMID 22278852›Full record

SynthesisClinical orthopaedics and related research2012

Which is the best alternative for displaced femoral neck fractures in the elderly?: A meta-analysis.

Hongwei Gao, Zhonghao Liu, Deguo Xing, Mingzhi Gong

Registry-linked trialAbstract readComparative StudyMeta-Analysis
In one paragraph

Synthesis in Clinical orthopaedics and related research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02362971 (External Validity of a Randomized Controlled Trial in Patients With a Femoral Neck Fracture), which is not on this map. Cited by 46 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed, 10 pooled it
8.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02362971 active not recruitingnot on this map

External Validity of a Randomized Controlled Trial in Patients With a Femoral Neck Fracture

TypeobservationalSponsorDanderyd HospitalRan2009 to 2027Enrolled900ConditionsFemoral Neck Fracture, Hip Fracture
3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 10 syntheses or guidelines pooled it, 109 citations in OpenAlex.

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  16. When would orthopaedic surgeons perform arthroplasty for a femoral neck fracture in an older adult?European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
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  19. Comparable results for the Femoral Neck System and three-screw fixation in femoral neck fracture treatment.OTA international : the open access journal of orthopaedic trauma · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Hongwei GaoDepartment of Orthopaedics, The Second Hospital of Shandong University, 247 Beiyuan Street, Shandong, 250033, Jinan, People's Republic of China.
Zhonghao Liu
Deguo Xing
Mingzhi Gong
Second Hospital of Shandong University · CNS.P.E.C.I.E.S. · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTreatment of displaced femoral neck fractures includes internal fixation and arthroplasty. However, whether arthroplasty or internal fixation is the primary treatment for displaced femoral neck fractures in elderly patients remains a subject for debate. The literature contains conflicting evidence regarding rates of mortality, revision surgery, major postoperative complications, and function in elderly patients with displaced femoral neck fractures treated either by internal fixation or arthroplasty (either hemiarthroplasty or THA). QUESTIONS/PURPOSE: We determined mortality, revision surgery rates, major surgical complications (which include infection, nonunion or early redisplacement, avascular necrosis, dislocation, loosening of the prosthesis, acetabular erosion, fracture below or around the implant, and other severe general complications such as deep vein thrombosis and pulmonary embolism), and function in patients treated with either internal fixation or arthroplasty for displaced femoral neck fractures in the elderly.

methodsWe searched PubMed, Embase, and the Cochrane Library for randomized controlled trials (RCTs) comparing internal fixation and arthroplasty. We identified 20 RCTs with 4508 patients meeting all the criteria for eligibility. We performed a meta-analysis of the major complications, reoperations, function, pain, and mortality.

resultsCompared with internal fixation, arthroplasty reduced the risk of the major complications (95% CI, 0.21-0.54 for 1 year; 95% CI, 0.16-0.31 for 5 years) and the incidence of reoperation 1 to 5 years after surgery (95% CI, 0.15-0.34 for 1 year; 95% CI, 0.08-0.24 for 5 years), and provided better pain relief (95% CI, 0.34-0.72). Function was superior (RR = 0.59; 95% CI, 0.44-0.79) for patients treated with arthroplasty than for patients treated by internal fixation. However, mortality 1 to 3 years after surgery was similar (95% CI, 0.96-1.23, p = 0.20 for 1 year; 95% CI, 0.91-1.17, p = 0.63 for 3 years).

conclusionsArthroplasty can reduce the risk of major complications and the incidence of reoperation compared with internal fixation, and provide better pain relief and function, but it does not reduce mortality. LEVEL OF EVIDENCE: Level II, prognostic study. See the Guidelines for Authors for a complete description of levels of evidence.

Indexed as

Arthroplasty, Replacement, HipFracture Fixation, InternalAgedAged, 80 and overFemoral Neck FracturesHumans

Identifiers

PMID22278852
PMCPMC3348330
OpenAlexW1972736977

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.