Evidence map›Paper›PMID 22278838›Full record

ArticleJournal of clinical microbiology2012

Evaluation of a high-throughput diagnostic system for detection of HIV-1 in dried blood spot samples from infants in Mozambique.

Ilesh V Jani, Jennifer Sabatier, Adolfo Vubil, Shambavi Subbarao, Dulce Bila, Amina de Sousa, Nédio Mabunda, Albert Garcia, Beth Skaggs, Dennis Ellenberger and 1 more

Abstract readComparative StudyEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ilesh V JaniInstituto Nacional de Saúde, Maputo, Mozambique.
Jennifer Sabatier
Adolfo Vubil
Shambavi Subbarao
Dulce Bila
Amina de Sousa
Nédio Mabunda
Albert Garcia
Beth Skaggs
Dennis Ellenberger
Artur Ramos

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We performed a comparative analysis between Roche Amplicor HIV-1 DNA test and CAPTAQ assay for the detection of HIV in 830 dried blood spot (DBS) pediatric samples collected in Mozambique. Our results demonstrated no statistical difference between these assays. The CAPTAQ assay approached nearly 100% repeatability/accuracy. The increased throughput of testing with minimal operator interference in performing the CAPTAQ assay clearly demonstrated that this method is an improvement over the Roche Amplicor HIV-1 DNA test, version 1.5.

Indexed as

Dried Blood Spot TestingHIV-1HIV InfectionsHumansInfantMolecular Diagnostic TechniquesMozambiqueReproducibility of ResultsSensitivity and Specificity

Identifiers

PMID22278838
PMCPMC3318546

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.