Evidence map›Paper›PMID 22278125›Full record

ArticleJournal of developmental and behavioral pediatrics : JDBP2012

Severity of the aggression/anxiety-depression/attention child behavior checklist profile discriminates between different levels of deficits in emotional regulation in youth with attention-deficit hyperactivity disorder.

Joseph Biederman, Carter R Petty, Helen Day, Rachel L Goldin, Thomas Spencer, Stephen V Faraone, Craig B H Surman, Janet Wozniak

Abstract readComparative Study
In one paragraph

Article in Journal of developmental and behavioral pediatrics : JDBP, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 1 synthesis or guideline pooled it, 128 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Joseph BiedermanClinical and Research Program in Pediatric Psychopharmacology and Adult ADHD, Massachusetts General Hospital, Pediatric Psychopharmacology Unit, Yawkey Center for Outpatient Care, Boston, MA, USA.
Carter R Petty
Helen Day
Rachel L Goldin
Thomas Spencer
Stephen V Faraone
Craig B H Surman
Janet Wozniak
Massachusetts General Hospital · US

Funding

OUTCOME OF ATTENTION DEFICIT HYPERACTIVITY DISORDERR01HD036317 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI BIEDERMAN, JOSEPH · 1998 to 2007
$4.0M
LONGITUDINAL FOLLOW UP OF ADHD GIRLS AND THEIR SIBLINGSR01MH050657 · NIMH · MASSACHUSETTS GENERAL HOSPITAL · PI BIEDERMAN, JOSEPH · 1993 to 2002
$1.5M
NICHD NIH HHS R01 HD036317NICHD NIH HHS R01 HD36317NIMH NIH HHS R01 MH050657NIMH NIH HHS R01 MH50657
6 · The paper itself

Abstract

objectiveWe examined whether severity scores (1 SD vs 2 SDs) of a unique profile of the Child Behavior Checklist (CBCL) consisting of the Anxiety/Depression, Aggression, and Attention (AAA) scales would help differentiate levels of deficits in children with attention-deficit hyperactivity disorder (ADHD). STUDY

designSubjects were 197 children with ADHD and 224 without ADHD. We defined deficient emotional self-regulation (DESR) as an aggregate cutoff score of >180 but <210 (1 SD) on the AAA scales of the CBCL (CBCL-DESR) and Severe Dysregulation as an aggregate cutoff score of ≥210 on the same scales (CBCL-Severe Dysregulation). All subjects were assessed with structured diagnostic interviews and a range of functional measures.

resultsThirty-six percent of children with ADHD had a positive CBCL-DESR profile versus 2% of controls (p < .001) and 19% had a positive CBCL-Severe Dysregulation profile versus 0% of controls (p < .001). The subjects positive for the CBCL-Severe Dysregulation profile differed selectively from those with the CBCL-DESR profile in having higher rates of unipolar and bipolar mood disorders, oppositional defiant and conduct disorders, psychiatric hospitalization at both baseline and follow-up assessments, and a higher rate of the CBCL-Severe Dysregulation in siblings. In contrast, the CBCL-DESR was associated with higher rates of comorbid disruptive behavior, anxiety disorders, and impaired interpersonal functioning compared with other ADHD children.

conclusionSeverity scores of the AAA CBCL profiles can help distinguish 2 groups of emotional regulation problems in children with ADHD.

Indexed as

AdolescentAdultAggressionAnxiety DisordersAttention Deficit Disorder with HyperactivityCase-Control StudiesChildDepressive DisorderFemaleFollow-Up StudiesHumansInterpersonal RelationsMaleParentsPsychiatric Status Rating ScalesSensitivity and Specificity

Identifiers

PMID22278125
PMCPMC3319866
OpenAlexW1983825283

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.