Evidence map›Paper›PMID 22277598›Full record

ReviewCurrent opinion in plant biology2012

Integrative systems biology: an attempt to describe a simple weed.

Louisa M Liberman, Rosangela Sozzani, Philip N Benfey

Abstract readReview
In one paragraph

Review in Current opinion in plant biology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. A Practical Guide to Inferring Multi-Omics Networks in Plant Systems.Methods in molecular biology (Clifton, N.J.) · 2023
    Article
  2. Data Management and Modeling in Plant Biology.Frontiers in plant science · 2021
    Review
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  14. Polyploidy and the evolution of complex traits.International journal of evolutionary biology · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Louisa M LibermanDepartment of Biology and Duke Center for Systems Biology, Duke University, Durham, NC, USA.
Rosangela Sozzani
Philip N Benfey

Funding

Project 6P50GM081883 · NIGMS · DUKE UNIVERSITY · PI BENFEY, PHILIP N · 2007 to 2012
$14.9M
MOLECULAR GENETIC ANALYSIS OF ROOT MORPHOGENESISR01GM043778 · NIGMS · ROCKEFELLER UNIVERSITY · PI BENFEY, PHILIP N · 1991 to 2017
$5.4M
NIGMS NIH HHS P50 GM081883NIGMS NIH HHS P50-GM081883NIGMS NIH HHS R01 GM043778NIGMS NIH HHS R01 GM-43778
6 · The paper itself

Abstract

Genome-scale studies hold great promise for revealing novel plant biology. Because of the complexity of these techniques, numerous considerations need to be made before embarking on a study. Here we focus on the Arabidopsis model system because of the wealth of available genome-scale data. Many approaches are available that provide genome-scale information regarding the state of a given organism (e.g. genomics, epigenomics, transcriptomics, proteomics, metabolomics interactomics, ionomics, phenomics, etc.). Integration of all of these types of data will be necessary for a comprehensive description of Arabidopsis. In this review we propose that 'triangulation' among transcriptomics, proteomics and metabolomics is a meaningful approach for beginning this integrative analysis and uncovering a systems level perspective of Arabidopsis biology.

Indexed as

ArabidopsisGenome, PlantGenomicsMetabolomicsProteomicsSystems Biology

Identifiers

PMID22277598
PMCPMC3435099

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.