Evidence map›Paper›PMID 22276626›Full record

SynthesisAnnals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc2012

Meta-analysis of p-wave dispersion values in healthy individuals: the influence of clinical characteristics.

Udi Nussinovitch

Abstract readMeta-Analysis
In one paragraph

Synthesis in Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Clinical Importance of P Wave Dispersion in Mitral Valve Prolapse.Journal of clinical practice and research · 2024
    Article
  3. Article
  4. Article
  5. Novel electrocardiographic indices of arrhythmogenesis and blood lead level.Annals of noninvasive electrocardiology : the official journal of the International Society for Holter and Noninvasive Electrocardiology, Inc · 2017
    Article
  6. Article
  7. Article
  8. Electrocardiographic P wave changes after thoracoscopic pulmonary vein isolation for atrial fibrillation.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2013
    Article
  9. Review
  10. Article
  11. Article
  12. The Effect of Synthetic Cannabinoids on P-Wave Dispersion: An Observational Study.Medical principles and practice : international journal of the Kuwait University, Health Science Centre
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Udi NussinovitchIsrael Naval Medical Institute, IDF Medical Corps, Haifa, Israel. enussi@yahoo.com

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundP-wave dispersion (Pd) is an appealing marker for predicting the risk of developing atrial fibrillation. At present, no definitive cutoff value has been determined as to the diagnosis of high-risk patients. Our aims were to evaluate P-wave parameters of healthy subjects published in the literature, determine normal range and weighted means of Pd and P-wave parameters, and investigate the influences of gender, age, and BMI on the weighted results.

methodsA systematic search of studies published in PubMed was conducted. Only studies which included control groups of healthy individuals were included.

resultsOf the 657 studies initially identified, 80 were eligible for inclusion. The total number of participants was 6,827. The highest reported Pd values were 58.56 ± 16.24 ms; the lowest were 7 ± 2.7 ms. The weighted mean was 33.46 ± 9.65 ms; weighted median was 32.2 ms. Gender and age were not found to be associated with significant influences on P-wave parameter values. High-normal BMI was not found to be associated with increased P-wave parameter values.

conclusionsPd, Pmax, and Pmin span a wide range of values in healthy individuals. Seemingly, abnormal values were often reported in healthy adults. The high variability of P-wave parameters in healthy individuals, and overlapping of the results with those reported for patients with increased risk for atrial fibrillation, might suggest that this technique has limited sensitivity and specificity. The variability between studies may stem from methodological issues and, therefore, there is a definite need for methodological standardization of Pd measurements.

Indexed as

ElectrocardiographyAdultAtrial FibrillationFemaleHeart Conduction SystemHumansMaleReference Values

Identifiers

PMID22276626
PMCPMC6932421

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.