ArticleIndian journal of endocrinology and metabolism2012
Obesity and cardiovascular risk in children and adolescents.
Article in Indian journal of endocrinology and metabolism, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers, 4 of them syntheses that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
58 citing papers in PubMed, 4 syntheses or guidelines pooled it, 148 citations in OpenAlex.
- Experiential Learning Interventions and Healthy Eating Outcomes in Children: A Systematic Literature Review.International journal of environmental research and public health · 2021Pooled it
- Green Space and Health in Mainland China: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- The impact of long-term school-based physical activity interventions on body mass index of primary school children - a meta-analysis of randomized controlled trials.BMC public health · 2016Pooled it
- Physical activity in overweight and obese adolescents: systematic review of the effects on physical fitness components and cardiovascular risk factors.Sports medicine (Auckland, N.Z.) · 2014Pooled it
- Efficacy of a Home-Based Parent Training-Focused Weight Management Intervention for Preschool Children: The DRIVE Randomized Controlled Pilot Trial.Journal of nutrition education and behavior · 2019Trial
- Clinical Effects of Rhus coriaria Fruits on Dyslipidemia308 in Adolescents: a Triple-blinded Randomized Placebo-controlled Trial.Medical archives (Sarajevo, Bosnia and Herzegovina) · 2014Trial
- Gut Microbiome-Hormone Interactions and Precision Fermentation in the Prevention of Early Cardiovascular Risk in Adolescents.International journal of molecular sciences · 2026Review
- Acute Effects of Exercise on Metabolic, Inflammatory, and Immune Markers in Adolescent Girls with Normal Weight or Overweight/Obesity.Sports (Basel, Switzerland) · 2026Article
- Didactic adaptation of basketball in physical education to reduce anxiety and emotional eating in adolescent girls with obesity: a randomized controlled trial.Frontiers in psychology · 2026Article
- Device-measured physical activity and adiposity in schoolchildren: a 30-week follow-up study.BMC medicine · 2025Article
- What Causes Premature Coronary Artery Disease?Current atherosclerosis reports · 2024Review
- A study on the intervention effect of a case management model that breaks through spatiotemporal characteristics in home-based phase II exercise rehabilitation post PCI.Frontiers in cardiovascular medicine · 2024Article
- The Uterine Environment and Childhood Obesity Risk: Mechanisms and Predictions.Current nutrition reports · 2023Review
- Combining multiaspect factors to predict the risk of childhood hypertension incidence.Journal of clinical hypertension (Greenwich, Conn.) · 2022Article
- Should We Be Screening for Ischaemic Heart Disease Earlier in Childhood?Children (Basel, Switzerland) · 2022Review
- Pre-pregnancy maternal BMI classification is associated with preschool childhood diet quality and childhood obesity in the Avon Longitudinal Study of Parents and Children.Public health nutrition · 2021Article
- Association of dietary intake, physical activity, and sedentary behaviours with overweight and obesity among 282,213 adolescents in 89 low and middle income to high-income countries.International journal of obesity (2005) · 2021Article
- Assessment of Anthropometric Indices for Optimal Cut-Offs for Obesity Screening in a South African Adolescent Population.Biology · 2021Article
- Australian School Stakeholders' Perceived Strategies for Preventing Adolescent Obesity.International journal of environmental research and public health · 2021Article
- Predictors of Newborn's Weight for Height: A Machine Learning Study Using Nationwide Multicenter Ultrasound Data.Diagnostics (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
1 author at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The global prevalence of overweight and obesity in children and adolescents has increased substantially over the past several decades. These trends are also visible in developing economies like India. Childhood obesity impacts all the major organ systems of the body and is well known to result in significant morbidity and mortality. Obesity in childhood and adolescence is associated with established risk factors for cardiovascular diseases and accelerated atherosclerotic processes, including elevated blood pressure (BP), atherogenic dyslipidemia, atherosclerosis, metabolic syndrome, type II diabetes mellitus, cardiac structural and functional changes and obstructive sleep apnea. Probable mechanisms of obesity-related hypertension include insulin resistance, sodium retention, increased sympathetic nervous system activity, activation of the renin-angiotensin-aldosterone system and altered vascular function. Adiposity promotes cardiovascular risk clustering during childhood and adolescence. Insulin resistance has a strong association with childhood obesity. A variety of proinflammatory mediators that are associated with cardiometabolic dysfunction are also known to be influenced by obesity levels. Obesity in early life promotes atherosclerotic disease in vascular structures such as the aorta and the coronary arteries. Childhood and adolescent adiposity has strong influences on the structure and function of the heart, predominantly of the left ventricle. Obesity compromises pulmonary function and increases the risk of sleep-disordered breathing and obstructive sleep apnea. Neglecting childhood and adolescent obesity will compromise the cardiovascular health of the pediatric population and is likely to result in a serious public health crisis in future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.