ArticleThe HUGO journal2011
The use of race, ethnicity and ancestry in human genetic research.
Article in The HUGO journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- A data model for population descriptors in genomic research.American journal of human genetics · 2025Review
- Advancing health equity in Nova Scotia by exploring gaps in healthcare delivery: a mixed methods protocol.Research in health services & regions · 2025Article
- Race, ethnicity, and ancestry reporting in genetic counseling research: A focused mapping review and synthesis.Journal of genetic counseling · 2025Review
- The association between experiences of racism and mental health on children and young people in the UK: rapid scoping review.BJPsych open · 2025Review
- Pharmacokinetics and pharmacogenomics of ribociclib in black patients with metastatic breast cancer the LEANORA study.NPJ breast cancer · 2024Article
- Social determinants of health but not global genetic ancestry predict dementia prevalence in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Ancestry: How researchers use it and what they mean by it.Frontiers in genetics · 2023Article
- A scoping review of guidelines for the use of race, ethnicity, and ancestry reveals widespread consensus but also points of ongoing disagreement.American journal of human genetics · 2022Article
- Recommendations on the use and reporting of race, ethnicity, and ancestry in genetic research: Experiences from the NHLBI TOPMed program.Cell genomics · 2022Article
- Alzheimer's disease biomarkers in Black and non-Hispanic White cohorts: A contextualized review of the evidence.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2022Review
- Human genetic admixture through the lens of population genomics.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022Review
- Use of race, ethnicity, and ancestry data in health research.PLOS global public health · 2022Review
- Co-designing genomics research with a large group of donor-conceived siblings.Research involvement and engagement · 2021Article
- Precision oncology: Directing genomics and pharmacogenomics toward reducing cancer inequities.Cancer cell · 2021Article
- Advancing equity, diversity, and inclusion in the American College of Neuropsychopharmacology (ACNP): advances, challenges, and opportunities to accelerate progress.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Predicting risk for Alcohol Use Disorder using longitudinal data with multimodal biomarkers and family history: a machine learning study.Molecular psychiatry · 2021Article
- We're in This Together: A Reflection on How Bioethics and Public Health Can Collectively Advance Scientific Efforts Towards Addressing Racism.Journal of bioethical inquiry · 2021Article
- The Use of Racial Categories in Precision Medicine Research.Ethnicity & disease · 2019Article
- The Role of Ethnicity and Environment in the Regulation of Response to Sensory Stimulus in Children: Protocol and Pilot Findings of a Neurophysiological Study.JMIR research protocols · 2018Article
- Possible relationship between common genetic variation and white matter development in a pilot study of preterm infants.Brain and behavior · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Post-Human Genome Project progress has enabled a new wave of population genetic research, and intensified controversy over the use of race/ethnicity in this work. At the same time, the development of methods for inferring genetic ancestry offers more empirical means of assigning group labels. Here, we provide a systematic analysis of the use of race/ethnicity and ancestry in current genetic research. We base our analysis on key published recommendations for the use and reporting of race/ethnicity which advise that researchers: explain why the terms/categories were used and how they were measured, carefully define them, and apply them consistently. We studied 170 population genetic research articles from high impact journals, published 2008-2009. A comparative perspective was obtained by aligning study metrics with similar research from articles published 2001-2004. Our analysis indicates a marked improvement in compliance with some of the recommendations/guidelines for the use of race/ethnicity over time, while showing that important shortfalls still remain: no article using 'race', 'ethnicity' or 'ancestry' defined or discussed the meaning of these concepts in context; a third of articles still do not provide a rationale for their use, with those using 'ancestry' being the least likely to do so. Further, no article discussed potential socio-ethical implications of the reported research. As such, there remains a clear imperative for highlighting the importance of consistent and comprehensive reporting on human populations to the genetics/genomics community globally, to generate explicit guidelines for the uses of ancestry and genetic ancestry, and importantly, to ensure that guidelines are followed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.