ArticleEcancermedicalscience2007
Does LigaSure reduce fluid drainage in axillary dissection? A randomized prospective clinical trial.
Article in Ecancermedicalscience, 2007. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.
- Contrast of Mastoscopic and Conventional Axillary Lymph Node Dissection of Patients With Breast Cancer: Meta-Analysis.Cancer control : journal of the Moffitt Cancer CenterPooled it
- The effectiveness of different flap-raising techniques for mastectomy in reducing the rate of complications: a network meta-analysis.BMC surgery · 2024Article
- Total Sealing Technique (TST) with a bipolar vessel sealing system reduces lymphorrhea and seroma formation for axillary lymph node dissection in primary breast cancer.Surgery open science · 2024Article
- Use of LigaSure vessel sealing system versus conventional axillary dissection in breast cancer patients: a retrospective comparative study.BMC surgery · 2022Article
- Evaluating HEmopatch® in Reducing Seroma-Related Complications following Axillary Lymph Node DIssection: A Pilot Study (HEIDI).Breast care (Basel, Switzerland) · 2022Article
- A Prospective Randomized Study to Compare Postoperative Drainage After Mastectomy Using Electrosurgical Bipolar Systems and Conventional Electro-Cautery.Journal of breast cancer · 2022Article
- Effect of autologous fibrin glue on seroma reduction after modified radical mastectomy for breast cancer: A randomized controlled trial.Annals of medicine and surgery (2012) · 2021Article
- Effectiveness of Cyanoacrylate in Reducing Seroma Formation in Breast Cancer Patients Post-Axillary Dissection: A Randomized Controlled Trial.Frontiers in oncology · 2020Article
- Advanced hemostasis in axillary lymph node dissection for locally advanced breast cancer: new technology devices compared in the prevention of seroma formation.BMC surgery · 2019Article
- Impact of the surgical modality for axillary lymph node dissection on postoperative drainage and seroma formation after total mastectomy.Patient safety in surgery · 2019Article
- Efficacy and safety of LigaSure™ small jaw instrument in thyroidectomy: a 1-year prospective observational study.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2018Observational
- Comparison of skin-sparing mastectomy using LigaSure™ Small Jaw and electrocautery.World journal of surgical oncology · 2017Article
- Modern lymphatic dissection techniques for preventing post renal transplant lymphocele.Clujul medical (1957) · 2017Article
- Seroma formation after breast cancer surgery: what we have learned in the last two decades.Journal of breast cancer · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAxillary lymph node dissection (ALND) is an integral part of breast cancer treatment. It is required in about 40-50% of patients. The placement of a drain in the axilla after an operation is current surgical practice. Short surgical stay programmes increase operating efficiency and reduce medical care costs, without compromising quality of care. LigaSure(™) is a new haemostatic device that uses bipolar energy to seal vessels. The aim of this study is to determine whether axillary dissection with LigaSure(™) reduces the time of wound drainage, the duration of surgical intervention and the volume of drainage after treatment. PATIENTS AND
methodsThis study is a prospective randomized controlled trial. A total of 100 women with breast cancer who needed axillary dissection were randomized into the LigaSure(™) or conventional axillary dissection group. Levels I to III lymph node dissection was performed. A closed suction drain was always placed in the axilla and removed after 6-8 days or when fluid amount was <60 cc in the previous 24 hours.
resultsTHERE WERE NO SIGNIFICANT DIFFERENCES BETWEEN THE TWO GROUPS WHEN CONSIDERING THE DURATION OF SURGICAL PROCEDURE: average duration was 70.7 ± 24.66 minutes for LigaSure(™) patients, while in the conventional dissection group the mean was 70.6 ± 22.47 minutes (p=0.98). Total amount of drained fluid was 624.49 cc in the LigaSure(™) axillary dissection group and 792.96 in the conventional ALND group; this difference did not achieve statistical significance (p=0.09); the duration of draining was also similar, with no statistical difference (p=0.15).
conclusionsThe present study did not show clear advantages in LigaSure(™) use for ALND, although it represents a good haemostatic device, especially in abdominal surgery.
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