Evidence map›Paper›PMID 22275712›Full record

Trial reportIEEE ... International Conference on Rehabilitation Robotics : [proceedings]2011

The relationship between the flexion synergy and stretch reflexes in individuals with chronic hemiparetic stroke.

Jacob G McPherson, Arno H A Stienen, Justin M Drogos, Julius P A Dewald

Open access · greenAbstract readClinical Trial
In one paragraph

Trial report in IEEE ... International Conference on Rehabilitation Robotics : [proceedings], 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Method for Quantification of Stretch Reflex Excitability During Ballistic Reaching.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2023
    Article
  5. Article
  6. Article
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  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 2 countries.

Jacob G McPhersonDept of Biomedical Engineering, Northwestern University, Evanston, IL, USA. jacobmcpherson@northwestern.edu
Arno H A Stienen
Justin M Drogos
Julius P A Dewald
Northwestern University · US

Funding

EFFECT OF NEURAL CONSTRAINTS ON MOVEMENT IN STROKER01HD039343 · NICHD · REHABILITATION INSTITUTE OF CHICAGO · PI JULIUS P DEWALD, JUN YAO · 2000 to 2026
$6.0M
Monoaminergic Drive and Discoordination Following StrokeR01NS054269 · NINDS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI DEWALD, JULIUS P · 2005 to 2008
$1.2M
NICHD NIH HHS R01 HD039343NICHD NIH HHS R01-HD039343NINDS NIH HHS R01 NS054269NINDS NIH HHS R01-NS054269
6 · The paper itself

Abstract

This study utilized a novel robotic device, the ACT-4D, to investigate the relationship between the flexion synergy and stretch reflexes in individuals with chronic hemiparetic stroke. Because the flexion synergy influences the amount of elbow flexor muscle activation present in the paretic limb during tasks requiring shoulder abduction loading, it was hypothesized that stretch reflexes may be modulated by expression of this abnormal muscle coactivation pattern. To test this hypothesis, the ACT-4D was used to enable 10 individuals with chronic hemiparetic stroke to generate varying amounts of shoulder abduction torque while concurrently receiving elbow extension position perturbations. It was found that increased expression of the flexion synergy led to greater reflex amplitudes as well as lower reflex velocity thresholds. The physiological basis of the flexion synergy is briefly discussed, as are the implications of the flexion synergy and stretch reflexes for purposeful movement.

Indexed as

Stroke RehabilitationElbow JointElectromyographyHumansRange of Motion, ArticularReflex, StretchRobotics

Identifiers

PMID22275712
PMCPMC6561470
OpenAlexW2149794533

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.