Evidence map›Paper›PMID 22275169›Full record

ArticleSocial cognitive and affective neuroscience2013

Rationality and emotionality: serotonin transporter genotype influences reasoning bias.

Melanie Stollstorff, Stephanie E Bean, Lindsay M Anderson, Joseph M Devaney, Chandan J Vaidya

Abstract read
In one paragraph

Article in Social cognitive and affective neuroscience, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Melanie StollstorffDepartment of Psychology and Neuroscience, UCB 345, University of Colorado Boulder, Boulder, CO 80309, USA. melanie.stollstorff@colorado.edu
Stephanie E Bean
Lindsay M Anderson
Joseph M Devaney
Chandan J Vaidya

Funding

NCMRR-DC Core Molecular & Functional Outcome Measures in Rehabilitation MedicineR24HD050846 · NICHD · CHILDREN'S RESEARCH INSTITUTE · PI KNOBLACH, SUSAN M · 2005 to 2014
$8.6M
Improved Diagnostic of the Muscular DystrophiesR01NS029525 · NINDS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI HOFFMAN, ERIC P. · 1991 to 2015
$6.5M
Integrating brain imaging and genetic analysis of ADHDR01MH065395 · NIMH · GEORGETOWN UNIVERSITY · PI VAIDYA, CHANDAN J · 2003 to 2007
$1.6M
Effects of dopaminergic genotypes on resting state connectivity relevant to execuR03MH086709 · NIMH · GEORGETOWN UNIVERSITY · PI VAIDYA, CHANDAN J · 2010 to 2011
$151k
NICHD NIH HHS NCMRR/NINDS 2R24HD050846-06NICHD NIH HHS R24 HD050846NIMH NIH HHS MH065395-01NIMH NIH HHS R01 MH065395NIMH NIH HHS R03 MH086709NINDS NIH HHS NINDS 5R01NS029525NINDS NIH HHS R01 NS029525
6 · The paper itself

Abstract

Reasoning often occurs under emotionally charged, opinion-laden circumstances. The belief-bias effect indexes the extent to which reasoning is based upon beliefs rather than logical structure. We examined whether emotional content increases this effect, particularly for adults genetically predisposed to be more emotionally reactive. SS/SL(G) carriers of the serotonin transporter genotype (5-HTTLPR) were less accurate selectively for evaluating emotional relational reasoning problems with belief-logic conflict relative to L(A)L(A) carriers. Trait anxiety was positively associated with emotional belief-bias, and the 5-HTTLPR genotype significantly accounted for the variance in this association. Thus, deductive reasoning, a higher cognitive ability, is sensitive to differences in emotionality rooted in serotonin neurotransmitter function.

Indexed as

LogicAdultAnxietyCognitionCultureEmotionsFemaleGenetic Predisposition to DiseaseGenotypeHumansMaleProblem SolvingSerotonin Plasma Membrane Transport ProteinsYoung AdultSerotonin Plasma Membrane Transport Proteins

Identifiers

PMID22275169
PMCPMC3624950

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.